| Literature DB >> 3359671 |
A Eklund1, K O Simola, M Ryynänen.
Abstract
The Robertsonian translocation 5(13;14)(p11;q11) was studied in three families with probable common ancestry in Eastern Finland. In the largest family the translocation has segregated through at least nine generations. The same family also included a female who was homozygous for t(13;14). No clear-cut effect of the translocation on fertility could be demonstrated and only one case of trisomy 13 was recorded in the offspring of t(13;14) carriers. The results are discussed, with implication for human chromosomal evolution.Entities:
Mesh：
Year: 1988 PMID： 3359671 DOI： 10.1111/j.1399-0004.1988.tb03415.x
Source DB: PubMed Journal: Clin Genet ISSN： 0009-9163 Impact factor: 4.438