Literature DB >> 335963

Chartreusin: production and microbiological assay.

L J Hanka, S A Gerpheide.   

Abstract

Chartreusin was produced in the fermentation liquors of Streptomyces chartreusis at peak concentrations of 200 to 300 mug/ml. The titers could be increased by 200 to 300% or more by incorporating d-fucose, a part of the chartreusin molecule, into the fermentation media. A microbiological assay with Sarcina lutea could detect concentrations of the drug of 0.5 to 1.0 mug/ml.

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Year:  1977        PMID: 335963      PMCID: PMC429977          DOI: 10.1128/AAC.12.5.571

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  1 in total

1.  Antitumor activity and preliminary drug disposition studies on chartreusin (NSC 5159).

Authors:  J P McGovren; G L Neil; S L Crampton; M I Robinson; J D Douros
Journal:  Cancer Res       Date:  1977-06       Impact factor: 12.701

  1 in total
  1 in total

Review 1.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

  1 in total

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