Literature DB >> 33595044

A class of water-soluble Fe(III) coordination complexes as T1-weighted MRI contrast agents.

Run Wang1, Lu An1, Jing He1, Mengmeng Li1, Jingjing Jiao1, Shiping Yang2.   

Abstract

Iron-based coordination complexes are showing increasing potential to be alternatives for T1-weighted magnetic resonance imaging (MRI) and contribute to the safety of gadolinium-based compounds. In this work, three water-soluble iron-based complexes constructed using catechol ligands exhibiting T1-weighted MRI contrast behavior are described. The longitudinal relaxivity (r1) increase from 0.88 to 1.43 mM-1 s-1 mainly depends on the sizes and the number of water molecules in the second and outer spheres around the discrete complexes.

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Year:  2021        PMID： 33595044     DOI： 10.1039/d0tb02716b

Source DB:  PubMed          Journal:  J Mater Chem B        ISSN： 2050-750X            Impact factor:   6.331


  3 in total

1.  Metal-Organic Polyhedron with Four Fe(III) Centers Producing Enhanced T1 Magnetic Resonance Imaging Contrast in Tumors.

Authors:  Gregory E Sokolow; Matthew R Crawley; Daniel R Morphet; Didar Asik; Joseph A Spernyak; A J Robert McGray; Timothy R Cook; Janet R Morrow
Journal:  Inorg Chem       Date:  2022-01-24       Impact factor: 5.436

2.  An iron-chelating sulfonamide identified from Drosophila-based screening for antipathogenic discovery.

Authors:  Yeon-Ji Yoo; In-Young Chung; Shivakumar S Jalde; Hyun-Kyung Choi; You-Hee Cho
Journal:  Virulence       Date:  2022-12       Impact factor: 5.428

Review 3.  Low-Molecular-Weight Fe(III) Complexes for MRI Contrast Agents.

Authors:  Shangjun Chen; Lu An; Shiping Yang
Journal:  Molecules       Date:  2022-07-18       Impact factor: 4.927
  3 in total

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