| Literature DB >> 33594262 |
He Wang1,2, Yan Li1,2, Mawsheng Chern3, Yong Zhu1,2, Ling-Li Zhang2, Jun-Hua Lu2, Xu-Pu Li2, Wen-Qiang Dang2, Xiao-Chun Ma2, Zhi-Rui Yang4, Sheng-Ze Yao4, Zhi-Xue Zhao1,2, Jing Fan1,2, Yan-Yan Huang1,2, Ji-Wei Zhang1,2, Mei Pu1,2, Jing Wang1,2, Min He1,2, Wei-Tao Li1,2, Xue-Wei Chen1,2, Xian-Jun Wu1,2, Shi-Gui Li1,2, Ping Li1,2, Yi Li4, Pamela C Ronald3, Wen-Ming Wang5,6.
Abstract
MicroRNA168 (miR168) is a key miRNA that targets Argonaute1 (AGO1), a major component of the RNA-induced silencing complex1,2. Previously, we reported that miR168 expression was responsive to infection by Magnaporthe oryzae, the causal agent of rice blast disease3. However, how miR168 regulates immunity to rice blast and whether it affects rice development remains unclear. Here, we report our discovery that the suppression of miR168 by a target mimic (MIM168) not only improves grain yield and shortens flowering time in rice but also enhances immunity to M. oryzae. These results were validated through repeated tests in rice fields in the absence and presence of rice blast pressure. We found that the miR168-AGO1 module regulates miR535 to improve yield by increasing panicle number, miR164 to reduce flowering time, and miR1320 and miR164 to enhance immunity. Our discovery demonstrates that changes in a single miRNA enhance the expression of multiple agronomically important traits.Entities:
Mesh：
Substances：
Year: 2021 PMID： 33594262 DOI： 10.1038/s41477-021-00852-x
Source DB: PubMed Journal: Nat Plants ISSN： 2055-0278 Impact factor: 15.793