Ruoyu Chao1, Chunli Wu1, Hongqiang An2, Bing Li1, Jianlin Wu1. 1. College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan. 2. Xintai Affiliated Hospital of Shandong First Medical University, Taian, Shandong Province, PR China.
Abstract
BACKGROUND: In recent years, the incidence of insomnia is increasing. However, the existing therapy methods for cannot fundamentally treat the disease. Meanwhile, Chinese patent medicine (CPM) plays an active role in the treatment of insomnia. However, there is no comparison and ranking of the efficacy of every CPM. Therefore, our study will use network meta-analysis to compare the efficacy of different CPM on insomnia, in order to provide evidence-based medical evidence for clinical treatment. METHODS: We will search CNKI, Wanfang, VIP, CBM, Pubmed, Cochrane Library, Embase for the randomized controlled trials of CPM in the treatment of insomnia (up to December 31, 2020). We will use RevMan5.3, Stata15.1 and ADDIS software for statistical analysis. We will draw the surface under cumulative ranking area to predict the order of efficacy. RESULTS: We aim to rank the efficacy and safety of different CPM for the treatment of insomnia. CONCLUSION: CPM plays a positive role in the treatment of insomnia and can provide evidence support for clinicians and patients. INPLASY REGISTRATION NUMBER: INPLASY2020120121.
BACKGROUND: In recent years, the incidence of insomnia is increasing. However, the existing therapy methods for cannot fundamentally treat the disease. Meanwhile, Chinese patent medicine (CPM) plays an active role in the treatment of insomnia. However, there is no comparison and ranking of the efficacy of every CPM. Therefore, our study will use network meta-analysis to compare the efficacy of different CPM on insomnia, in order to provide evidence-based medical evidence for clinical treatment. METHODS: We will search CNKI, Wanfang, VIP, CBM, Pubmed, Cochrane Library, Embase for the randomized controlled trials of CPM in the treatment of insomnia (up to December 31, 2020). We will use RevMan5.3, Stata15.1 and ADDIS software for statistical analysis. We will draw the surface under cumulative ranking area to predict the order of efficacy. RESULTS: We aim to rank the efficacy and safety of different CPM for the treatment of insomnia. CONCLUSION: CPM plays a positive role in the treatment of insomnia and can provide evidence support for clinicians and patients. INPLASY REGISTRATION NUMBER: INPLASY2020120121.
Authors: Denise C Jarrin; Pasquale K Alvaro; Marc-André Bouchard; Stephanie D Jarrin; Christopher L Drake; Charles M Morin Journal: Sleep Med Rev Date: 2018-02-16 Impact factor: 11.609
Authors: Brian Hutton; Georgia Salanti; Deborah M Caldwell; Anna Chaimani; Christopher H Schmid; Chris Cameron; John P A Ioannidis; Sharon Straus; Kristian Thorlund; Jeroen P Jansen; Cynthia Mulrow; Ferrán Catalá-López; Peter C Gøtzsche; Kay Dickersin; Isabelle Boutron; Douglas G Altman; David Moher Journal: Ann Intern Med Date: 2015-06-02 Impact factor: 25.391