Literature DB >> 33591974

Examining the Ugandan health system's readiness to deliver rheumatic heart disease-related services.

Emma Ndagire1,2, Yoshito Kawakatsu3, Hadija Nalubwama1, Jenifer Atala1, Rachel Sarnacki2, Jafesi Pulle1, Rakeli Kyarimpa1, Rachel Mwima1, Rosemary Kansiime1, Emmy Okello1, Peter Lwabi1, Andrea Beaton4,5, Craig Sable2,6, David Watkins3,7.   

Abstract

BACKGROUND: In 2018, the World Health Assembly mandated Member States to take action on rheumatic heart disease (RHD), which persists in countries with weak health systems. We conducted an assessment of the current state of RHD-related healthcare in Uganda. METHODOLOGY/PRINCIPAL
FINDINGS: This was a mixed-methods, deductive simultaneous design study conducted in four districts of Uganda. Using census sampling, we surveyed health facilities in each district using an RHD survey instrument that was modeled after the WHO SARA tool. We interviewed health workers with experience managing RHD, purposively sampling to ensure a range of qualification and geographic variation. Our final sample included 402 facilities and 36 health workers. We found major gaps in knowledge of clinical guidelines and availability of diagnostic tests. Antibiotics used in RHD prevention were widely available, but cardiovascular medications were scarce. Higher levels of service readiness were found among facilities in the western region (Mbarara district) and private facilities. Level III health centers were the most prepared for delivering secondary prevention. Health worker interviews revealed that limited awareness of RHD at the district level, lack of diagnostic tests and case management registries, and absence of clearly articulated RHD policies and budget prioritization were the main barriers to providing RHD-related healthcare.
CONCLUSIONS/SIGNIFICANCE: Uganda's readiness to implement the World Health Assembly RHD Resolution is low. The forthcoming national RHD strategy must focus on decentralizing RHD diagnosis and prevention to the district level, emphasizing specialized training of the primary healthcare workforce and strengthening supply chains of diagnostics and essential medicines.

Entities:  

Year:  2021        PMID: 33591974      PMCID: PMC7909659          DOI: 10.1371/journal.pntd.0009164

Source DB:  PubMed          Journal:  PLoS Negl Trop Dis        ISSN: 1935-2727


  20 in total

1.  Rheumatic heart disease: social and economic dimensions.

Authors:  Katharine A Robertson; Bongani M Mayosi
Journal:  S Afr Med J       Date:  2008-10

Review 2.  Rheumatic Heart Disease Worldwide: JACC Scientific Expert Panel.

Authors:  David A Watkins; Andrea Z Beaton; Jonathan R Carapetis; Ganesan Karthikeyan; Bongani M Mayosi; Rosemary Wyber; Magdi H Yacoub; Liesl J Zühlke
Journal:  J Am Coll Cardiol       Date:  2018-09-18       Impact factor: 24.094

3.  WHO Resolution on rheumatic heart disease.

Authors:  Alastair White
Journal:  Eur Heart J       Date:  2018-12-21       Impact factor: 29.983

4.  Community study to uncover the full spectrum of rheumatic heart disease in Uganda.

Authors:  Amy Scheel; Isaac Ssinabulya; Twalib Aliku; Tyler Bradley-Hewitt; Alexa Clauss; Sarah Clauss; Lexi Crawford; Alyssa DeWyer; Mary T Donofrio; Marni Jacobs; Jennifer Klein; Teresa E Moore; Emmy Okello; Janet Scheel; Rebekah Shaw; Craig Sable; Peter Lwabi; David A Watkins; Andrea Beaton
Journal:  Heart       Date:  2018-08-01       Impact factor: 5.994

5.  Characteristics, complications, and gaps in evidence-based interventions in rheumatic heart disease: the Global Rheumatic Heart Disease Registry (the REMEDY study).

Authors:  Liesl Zühlke; Mark E Engel; Ganesan Karthikeyan; Sumathy Rangarajan; Pam Mackie; Blanche Cupido; Katya Mauff; Shofiqul Islam; Alexia Joachim; Rezeen Daniels; Veronica Francis; Stephen Ogendo; Bernard Gitura; Charles Mondo; Emmy Okello; Peter Lwabi; Mohammed M Al-Kebsi; Christopher Hugo-Hamman; Sahar S Sheta; Abraham Haileamlak; Wandimu Daniel; Dejuma Y Goshu; Senbeta G Abdissa; Araya G Desta; Bekele A Shasho; Dufera M Begna; Ahmed ElSayed; Ahmed S Ibrahim; John Musuku; Fidelia Bode-Thomas; Basil N Okeahialam; Olukemi Ige; Christopher Sutton; Rajeev Misra; Azza Abul Fadl; Neil Kennedy; Albertino Damasceno; Mahmoud Sani; Okechukwu S Ogah; Taiwo Olunuga; Huda H M Elhassan; Ana Olga Mocumbi; Abiodun M Adeoye; Phindile Mntla; Dike Ojji; Joseph Mucumbitsi; Koon Teo; Salim Yusuf; Bongani M Mayosi
Journal:  Eur Heart J       Date:  2014-11-25       Impact factor: 29.983

6.  Prevention of rheumatic fever in Costa Rica.

Authors:  A Arguedas; E Mohs
Journal:  J Pediatr       Date:  1992-10       Impact factor: 4.406

7.  The utility of handheld echocardiography for early diagnosis of rheumatic heart disease.

Authors:  Andrea Beaton; Twalib Aliku; Emmy Okello; Sulaiman Lubega; Robert McCarter; Peter Lwabi; Craig Sable
Journal:  J Am Soc Echocardiogr       Date:  2013-10-30       Impact factor: 5.251

8.  The WHF Roadmap for Reducing CV Morbidity and Mortality Through Prevention and Control of RHD.

Authors:  Benjamin Palafox; Ana Olga Mocumbi; R Krishna Kumar; Sulafa K M Ali; Elizabeth Kennedy; Abraham Haileamlak; David Watkins; Kadia Petricca; Rosemary Wyber; Patrick Timeon; Jeremiah Mwangi
Journal:  Glob Heart       Date:  2017-03-20

9.  Prevention and control of rheumatic fever and rheumatic heart disease: the Cuban experience (1986-1996-2002).

Authors:  P Nordet; R Lopez; A Dueñas; L Sarmiento
Journal:  Cardiovasc J Afr       Date:  2008 May-Jun       Impact factor: 1.167

10.  Cost-Effectiveness of Rheumatic Heart Disease Echocardiographic Screening in Brazil: Data from the PROVAR+ Study: Cost-effectiveness of RHD screening in Brazil.

Authors:  Jasper Ubels; Craig Sable; Andrea Z Beaton; Maria Carmo P Nunes; Kaciane K B Oliveira; Lara C Rabelo; Isabella M Teixeira; Gabriela Z L Ruiz; Letícia Maria M Rabelo; Alison R Tompsett; Antonio Luiz P Ribeiro; Klas-Göran Sahlen; Bruno R Nascimento
Journal:  Glob Heart       Date:  2020-02-20
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  4 in total

1.  Community Perspectives on Primary Prevention of Rheumatic Heart Disease in Uganda.

Authors:  Hadija Nalubwama; Emma Ndagire; Rachel Sarnacki; Jenifer Atala; Andrea Beaton; Rosemary Kansiime; Rachel Mwima; Emmy Okello; David Watkins
Journal:  Glob Heart       Date:  2022-01-20

2.  Modelling study of the ability to diagnose acute rheumatic fever at different levels of the Ugandan healthcare system.

Authors:  Emma Ndagire; Nicholas Ollberding; Rachel Sarnacki; Murali Meghna; Jafesi Pulle; Jenifer Atala; Collins Agaba; Rosemary Kansiime; Asha Bowen; Chris T Longenecker; Linda Oyella; Joselyn Rwebembera; Emmy Okello; Tom Parks; Huaiyu Zang; Jonathan Carapetis; Craig Sable; Andrea Z Beaton
Journal:  BMJ Open       Date:  2022-03-22       Impact factor: 2.692

Review 3.  Recent Advances in the Rheumatic Fever and Rheumatic Heart Disease Continuum.

Authors:  Joselyn Rwebembera; Bruno Ramos Nascimento; Neema W Minja; Sarah de Loizaga; Twalib Aliku; Luiza Pereira Afonso Dos Santos; Bruno Fernandes Galdino; Luiza Silame Corte; Vicente Rezende Silva; Andrew Young Chang; Walderez Ornelas Dutra; Maria Carmo Pereira Nunes; Andrea Zawacki Beaton
Journal:  Pathogens       Date:  2022-01-28

4.  Standardization of Epidemiological Surveillance of Acute Rheumatic Fever.

Authors:  Amy Scheel; Andrea Z Beaton; Judith Katzenellenbogen; Tom Parks; Kate M Miller; Thomas Cherian; Chris A Van Beneden; Jeffrey W Cannon; Hannah C Moore; Asha C Bowen; Jonathan R Carapetis
Journal:  Open Forum Infect Dis       Date:  2022-09-15       Impact factor: 4.423

  4 in total

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