| Literature DB >> 33591436 |
Kelly Jensen1,2,3, Sassan Noazin4, Leandra Bitterfeld5,6, Andrea Carcelen7, Natalia I Vargas-Cuentas8, Daniela Hidalgo8,9, Alejandra Valenzuela8, Avid Roman-Gonzalez8, Casey Krebs10, Vincent Clement9, Cody Nolan11, Franklin Barrientos8, Ardi Knobel Mendoza12, Paola Noriega-Donis13, Claudia Palacios8, Andrea Ramirez8, Macarena Vittet8, Emil Hafeez7, Mariana Torres-Viso14, Myriam Velarde15, Lawrence H Moulton7, Michael D Powers10,14, Robert H Gilman7, Mirko Zimic8.
Abstract
Most children with autism spectrum disorder (ASD), in resource-limited settings (RLS), are diagnosed after the age of four. Our work confirmed and extended results of Pierce that eye tracking could discriminate between typically developing (TD) children and those with ASD. We demonstrated the initial 15 s was at least as discriminating as the entire video. We evaluated the GP-MCHAT-R, which combines the first 15 s of manually-coded gaze preference (GP) video with M-CHAT-R results on 73 TD children and 28 children with ASD, 36-99 months of age. The GP-MCHAT-R (AUC = 0.89 (95%CI: 0.82-0.95)), performed significantly better than the MCHAT-R (AUC = 0.78 (95%CI: 0.71-0.85)) and gaze preference (AUC = 0.76 (95%CI: 0.64-0.88)) alone. This tool may enable early screening for ASD in RLS.Entities:
Keywords: ASD diagnosis; Autism spectrum disorder; Developmental disorder; Eye tracking; Gaze preference
Mesh：
Year: 2021 PMID： 33591436 PMCID： PMC7954728 DOI： 10.1007/s10803-021-04878-0
Source DB: PubMed Journal: J Autism Dev Disord ISSN： 0162-3257