Literature DB >> 33591211

The rate of COVID-19 and associated mortality after elective hip and knee arthroplasty prior to cessation of elective services in UK.

Nicholas D Clement1,2, Andrew J Hall1, Nardeen Kader2, Benjamin Ollivere3, Sam Oussedik4, Deiary F Kader2, David J Deehan5, Andrew D Duckworth1,6.   

Abstract

AIMS: The primary aim was to assess the rate of postoperative COVID-19 following hip and knee arthroplasty performed in March 2020 in the UK. The secondary aims were to assess whether there were clinical factors associated with COVID-19 status, the mortality rate of patients with COVID-19, and the rate of potential COVID-19 in patients not presenting to healthcare services.
METHODS: A multicentre retrospective study was conducted of patients undergoing hip or knee arthroplasty during the first wave of the COVID-19 pandemic (1 March 2020 to 31 March 2020) with a minimum of 60 days follow-up. Patient demographics, American Society of Anesthesiologists grade, procedure type, primary or revision, length of stay (LOS), COVID-19 test status, and postoperative mortality were recorded. A subgroup of patients (n = 211) who had not presented to healthcare services after discharge were contacted and questioned as to whether they had symptoms of COVID-19.
RESULTS: Five (0.5%) of 1,073 patients who underwent hip or knee arthroplasty tested positive for SARS-CoV-2 postoperatively. When adjusting for confounding factors, increasing LOS (p = 0.022) was the only significant factor associated with developing COVID-19 following surgery and a stay greater than three days was a reliable predictor with an area under the curve of 81% (p = 0.018). There were three (0.3%) deaths in the study cohort and the overall mortality rate attributable to COVID-19 was 0.09% (n = 1/1,073), with one (20%) of the five patients with COVID-19 dying postoperatively. Of the 211 patients contacted, two had symptoms within two to 14 days postoperatively with a positive predictive value of 31% and it was therefore estimated that one patient may have had undiagnosed COVID-19.
CONCLUSION: The rate of postoperative COVID-19 was 0.5% and may have been as high as 1% when accounting for those patients not presenting to healthcare services, which was similar to the estimated population prevalence during the study period. The overall mortality rate secondary to COVID-19 was low (0.09%), however the mortality rate for those patients developing COVID-19 was 20%. Cite this article: Bone Joint J 2021;103-B(4):681-688.

Entities:  

Keywords:  Arthroplasty; COVID-19; Elective; Hip; Knee; Mortality

Mesh:

Year:  2021        PMID: 33591211     DOI: 10.1302/0301-620X.103B.BJJ-2020-1776.R1

Source DB:  PubMed          Journal:  Bone Joint J        ISSN: 2049-4394            Impact factor:   5.082


  6 in total

1.  The IMPACT of COVID-19 on trauma & orthopaedic surgery provides lessons for future communicable disease outbreaks : minimum reporting standards, risk scores, fragility trauma services, and global collaboration.

Authors:  Andrew J Hall; Nick D Clement; Alasdair M J MacLullich; A Hamish R W Simpson; Tim O White; Andrew D Duckworth
Journal:  Bone Joint Res       Date:  2022-06       Impact factor: 4.410

2.  National operating volume for primary hip and knee arthroplasty in the COVID-19 era: a study utilizing the Scottish arthroplasty project dataset.

Authors:  Liam Z Yapp; Jon V Clarke; Matthew Moran; A Hamish R W Simpson; Chloe E H Scott
Journal:  Bone Jt Open       Date:  2021-03

3.  Resuming elective orthopaedic services during the COVID-19 pandemic : our experience.

Authors:  Rongkagorn Chuntamongkol; Rebekah Meen; Sophie Nash; Nicholas E Ohly; Jon Clarke; Nicholas Holloway
Journal:  Bone Jt Open       Date:  2021-11

4.  IMPACT-Global Hip Fracture Audit: Nosocomial infection, risk prediction and prognostication, minimum reporting standards and global collaborative audit: Lessons from an international multicentre study of 7,090 patients conducted in 14 nations during the COVID-19 pandemic.

Authors:  Andrew J Hall; Nicholas D Clement; Cristina Ojeda-Thies; Alasdair Mj MacLullich; Giuseppe Toro; Antony Johansen; Tim O White; Andrew D Duckworth
Journal:  Surgeon       Date:  2022-03-28       Impact factor: 2.632

5.  COVID-19 infection rate after urgent versus elective total hip replacement among unvaccinated individuals: A multicenter prospective cohort amid the COVID-19 pandemic.

Authors:  Seyed Peyman Mirghaderi; Erfan Sheikhbahaei; Maryam Salimi; Seyed Reza Mirghaderi; Negar Ahmadi; Alireza Moharrami; Mehdi Motififard; Seyed Mohammad Javad Mortazavi
Journal:  Ann Med Surg (Lond)       Date:  2022-08-01

6.  COVID-19 during the index hospital admission confers a 'double-hit' effect on hip fracture patients and is associated with a two-fold increase in 1-year mortality risk.

Authors:  Andrew J Hall; Nicholas D Clement; Alasdair M J MacLullich; Timothy O White; Andrew D Duckworth
Journal:  Musculoskeletal Care       Date:  2022-08-05
  6 in total

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