Literature DB >> 33590301

CT-derived sarcopenia should not preclude surgical stabilization of traumatic rib fractures.

Derrick A Doolittle1, Matthew C Hernandez2, Francis I Baffour3, Michael R Moynagh3, Naoki Takahashi3, Adam T Froemming3, Katrina N Glazebrook3, Brian D Kim2.   

Abstract

BACKGROUND: Rib fractures are associated with considerable morbidity and mortality. Surgical stabilization of rib fractures (SSRF) can be performed to mitigate complications. Sarcopenia is in general known to be associated with poor clinical outcomes. We investigated if sarcopenia impacted number of days of mechanical ventilation, intensive care unit (ICU) stay, and total hospital stay in patients who underwent SSRF.
METHODS: A retrospective single institutional review was performed including patients who underwent SSRF (2009-2017). Skeletal muscle index (SMI) was semiautomatically calculated at the L3 spinal level on computed tomography (CT) images and normalized by patient height. Sarcopenia was defined as SMI < 55 cm2/m2 in males and < 39 cm2/m2 in females. Demographics, operative details, and postoperative outcomes were reviewed. Univariate and multivariate analyses were performed.
RESULTS: Of 238 patients, 88 (36.9%) had sarcopenia. There was no significant difference in number of days of mechanical ventilation (2.8 ± 4.9 versus 3.1 ± 4.3, p = 0.304), ICU stay (5.9 ± 6.5 versus 4.9 ± 5.7 days, p = 0.146), or total hospital stay (13.3 ± 7.2 versus 12.9 ± 8.2 days, p = 0.183) between sarcopenic and nonsarcopenic patients. Sarcopenic patients demonstrated increased modified frailty index scores (1.5 ± 1.1 versus 0.9 ± 0.9, p < 0.001) compared to nonsarcopenic patients.
CONCLUSIONS: For patients who underwent SSRF for rib fractures, sarcopenia did not increase the number of days of mechanical ventilation, ICU stay, or total hospital stay. Sarcopenia should not preclude the utilization of SSRF in these patients.

Entities:  

Keywords:  Length of stay; Muscle (skeletal); Rib fractures; Sarcopenia; Tomography (x-ray computed)

Mesh:

Year:  2021        PMID: 33590301      PMCID: PMC7884563          DOI: 10.1186/s41747-021-00206-4

Source DB:  PubMed          Journal:  Eur Radiol Exp        ISSN: 2509-9280


  31 in total

1.  Sarcopenia increases risk of long-term mortality in elderly patients undergoing emergency abdominal surgery.

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Journal:  J Trauma Acute Care Surg       Date:  2017-12       Impact factor: 3.313

2.  Sarcopenia and mortality after liver transplantation.

Authors:  Michael J Englesbe; Shaun P Patel; Kevin He; Raymond J Lynch; Douglas E Schaubel; Calista Harbaugh; Sven A Holcombe; Stewart C Wang; Dorry L Segev; Christopher J Sonnenday
Journal:  J Am Coll Surg       Date:  2010-06-26       Impact factor: 6.113

3.  Decreased Skeletal Muscle Mass is Associated with an Increased Risk of Mortality after Radical Nephrectomy for Localized Renal Cell Cancer.

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Journal:  J Urol       Date:  2015-08-18       Impact factor: 7.450

4.  New 5-Factor Modified Frailty Index Using American College of Surgeons NSQIP Data.

Authors:  Sneha Subramaniam; Jeffrey J Aalberg; Rainier P Soriano; Celia M Divino
Journal:  J Am Coll Surg       Date:  2017-11-16       Impact factor: 6.113

5.  Pulmonary contusions: quantifying the lesions on chest X-ray films and the factors affecting prognosis.

Authors:  J G Tyburski; J D Collinge; R F Wilson; S R Eachempati
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Authors:  Michael S Sabel; Jay Lee; Shijie Cai; Michael J Englesbe; Stephen Holcombe; Stewart Wang
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7.  Surgical rib fixation for flail chest deformity improves liberation from mechanical ventilation.

Authors:  Andrew R Doben; Evert A Eriksson; Chadrick E Denlinger; Stuart M Leon; Deborah J Couillard; Samir M Fakhry; Christian T Minshall
Journal:  J Crit Care       Date:  2013-09-24       Impact factor: 3.425

8.  Computed tomography measured psoas density predicts outcomes in trauma.

Authors:  Taehwan Yoo; Wilson D Lo; David C Evans
Journal:  Surgery       Date:  2017-05-24       Impact factor: 3.982

9.  Cancer cachexia in the age of obesity: skeletal muscle depletion is a powerful prognostic factor, independent of body mass index.

Authors:  Lisa Martin; Laura Birdsell; Neil Macdonald; Tony Reiman; M Thomas Clandinin; Linda J McCargar; Rachel Murphy; Sunita Ghosh; Michael B Sawyer; Vickie E Baracos
Journal:  J Clin Oncol       Date:  2013-03-25       Impact factor: 44.544

10.  The relationship between body composition and response to neoadjuvant chemotherapy in women with operable breast cancer.

Authors:  Egidio Del Fabbro; Henrique Parsons; Carla L Warneke; Kalyan Pulivarthi; Jennifer K Litton; Rony Dev; Shana L Palla; Abenaa Brewster; Eduardo Bruera
Journal:  Oncologist       Date:  2012-08-17
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  1 in total

Review 1.  Prevalence and prognostic value of preexisting sarcopenia in patients with mechanical ventilation: a systematic review and meta-analysis.

Authors:  Tingting Jiang; Taiping Lin; Xiaoyu Shu; Quhong Song; Miao Dai; Yanli Zhao; Li Huang; Xiangping Tu; Jirong Yue
Journal:  Crit Care       Date:  2022-05-16       Impact factor: 19.334

  1 in total

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