| Literature DB >> 33589389 |
William Y Raynor1, Austin J Borja2, Emily C Hancin3, Thomas J Werner4, Abass Alavi4, Mona-Elisabeth Revheim5.
Abstract
PET imaging with 18F-sodium fluoride (NaF), combined with computed tomography or magnetic resonance, is a sensitive method of assessing bone turnover. Although NaF-PET is gaining popularity in detecting prostate cancer metastases to bone marrow, osseous changes represent secondary effects of cancer cell growth. PET tracers more appropriate for assessing prostate cancer metastases directly portray malignant activity and include 18F-fluciclovine and prostatic specific membrane antigen ligands. Recent studies investigating NaF-PET suggest utility in the assessment of benign musculoskeletal disorders. Emerging applications in assessing traumatic injuries, joint disease, back pain, orthopedic complications, and metabolic bone disease are discussed.Entities:
Keywords: Ankylosing spondylitis; Arthroplasty; Fracture; Infection; Osteoarthritis; Osteoporosis; Osteosarcoma; Temporomandibular disorder
Year: 2021 PMID： 33589389 DOI： 10.1016/j.cpet.2020.12.006
Source DB: PubMed Journal: PET Clin ISSN： 1556-8598