Literature DB >> 3358756

Glomeruli from ischemic rat kidneys produce increased amounts of platelet activating factor.

A López-Farré1, M Torralbo, J M López-Novoa.   

Abstract

The production of Platelet Activating Factor (PAF-acether) by glomeruli isolated from rats subjected to a 60 min renal ischemia has been studied. PAF-acether has been purified by Sep-Pak columns and measured by its ability to release serotonin from previously loaded rabbit platelets. Glomeruli from ischemic kidneys had higher amounts of PAF-acether activity than glomeruli from sham operated rats. These data suggest a role for PAF-acether in the renal functional alterations induced by renal ischemia.

Entities:  

Mesh：

Substances：

Year:  1988        PMID： 3358756     DOI： 10.1016/s0006-291x(88)80689-2

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  7 in total

1.  Attenuation of folic acid-induced renal inflammatory injury in platelet-activating factor receptor-deficient mice.

Authors:  Kent Doi; Koji Okamoto; Kousuke Negishi; Yoshifumi Suzuki; Akihide Nakao; Toshiro Fujita; Akiko Toda; Takehiko Yokomizo; Yoshihiro Kita; Yasuyuki Kihara; Satoshi Ishii; Takao Shimizu; Eisei Noiri
Journal:  Am J Pathol       Date:  2006-05       Impact factor: 4.307

2.  Dexamethasone-induced gastric mucosal damage in the rat: possible role of platelet-activating factor.

Authors:  J G Filep; F Hermán; E Földes-Filep; F Schneider; P Braquet
Journal:  Br J Pharmacol       Date:  1992-04       Impact factor: 8.739

3.  Plasma mediated neutrophil stimulation during coronary angioplasty: autocrine effect of platelet activating factor.

Authors:  T Siminiak; D J O'Gorman; M Shahi; D Hackett; D J Sheridan
Journal:  Br Heart J       Date:  1995-12

4.  A role for endothelin in the maintenance of post-ischaemic renal failure in the rat.

Authors:  A López-Farré; D Gómez-Garre; F Bernabeu; J M López-Novoa
Journal:  J Physiol       Date:  1991-12       Impact factor: 5.182

Review 5.  Significance of platelet-activating factor in mesenteric ischemia-reperfusion.

Authors:  J Filep; P Braquet; T Mózes
Journal:  Lipids       Date:  1991-12       Impact factor: 1.880

6.  Platelet-activating factor may mediate dexamethasone-induced gastric damage in the rat.

Authors:  J Filep; F Hermán; P Braquet
Journal:  Lipids       Date:  1991-12       Impact factor: 1.880

7.  Effect of platelet activating factor antagonist treatment on gentamicin nephrotoxicity.

Authors:  A Rodriguez-Barbero; E Bosque; L Rivas-Cabaero; M Arévalo; J M López-Novoa
Journal:  Mediators Inflamm       Date:  1992       Impact factor: 4.711
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.