Literature DB >> 33586014

Changes in antimicrobial resistance and outcomes of health care-associated infections.

Mehtap Aydın1, Emel Azak2, Hüseyin Bilgin3, Sirin Menekse4, Ali Asan5, Habibe Tülin Elmaslar Mert6, Zerrin Yulugkural6, Lutfiye Nilsun Altunal7, Çiğdem Ataman Hatipoğlu8, Gunay Tuncer Ertem8, Elif Sargın Altunok9, Melike Hamiyet Demirkaya10, Sevil Alkan Çeviker11, Fethiye Akgul12, Zeynep Memis13, Petek Konya14, Alpay Azap15, Gule Aydin15, Derya Korkmaz16, Zehra Çagla Karakoç17, Derya Yapar18, Faruk Karakecili19, Ozgur Gunal20, Siran Keske21, Mahir Kapmaz21, Cigdem Kader22, Aslıhan Demirel23, Önder Ergönül21.   

Abstract

To describe the change in the epidemiology of health care-associated infections (HAI), resistance and predictors of fatality we conducted a nationwide study in 24 hospitals between 2015 and 2018. The 30-day fatality rate was 22% in 2015 and increased to 25% in 2018. In BSI, a significant increasing trend was observed for Candida and Enterococcus. The highest rate of 30-day fatality was detected among the patients with pneumonia (32%). In pneumonia, Pseudomonas infections increased in 2018. Colistin resistance increased and significantly associated with 30-day fatality in Pseudomonas infections. Among S. aureus methicillin, resistance increased from 31 to 41%.
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.

Entities:  

Keywords:  Blood stream infections; Colistin resistance; Health care; associated infections

Year:  2021        PMID: 33586014     DOI: 10.1007/s10096-020-04140-y

Source DB:  PubMed          Journal:  Eur J Clin Microbiol Infect Dis        ISSN: 0934-9723            Impact factor:   3.267


  2 in total

1.  Challenges, Issues and Warnings from CLSI and EUCAST Working Group on Polymyxin Susceptibility Testing.

Authors:  Yamuna Devi Bakthavatchalam; Balaji Veeraraghavan
Journal:  J Clin Diagn Res       Date:  2017-08-01

2.  Effect of initial antifungal therapy on mortality among patients with bloodstream infections with different Candida species and resistance to antifungal agents: A multicentre observational study by the Turkish Fungal Infections Study Group.

Authors:  Özlem Doğan; Ayşegül Yeşilkaya; Şirin Menekşe; Özlem Güler; Çağla Karakoç; Güle Çınar; Mahir Kapmaz; Mehtap Aydın; Şiran Keske; Suzan Şahin; Demet Hacıseyitoğlu; Demet Yalçın; Süda Tekin; Nazlı Ataç; Özgür Albayrak; Ekin Deniz Aksu; Füsun Can; Önder Ergönül
Journal:  Int J Antimicrob Agents       Date:  2020-04-24       Impact factor: 5.283

  2 in total
  2 in total

1.  Design, Characterization, and Antibacterial Performance of MAPLE-Deposited Coatings of Magnesium Phosphate-Containing Silver Nanoparticles in Biocompatible Concentrations.

Authors:  Denisa Alexandra Florea; Valentina Grumezescu; Alexandra Cătălina Bîrcă; Bogdan Ștefan Vasile; Mihaela Mușat; Cristina Chircov; Miruna S Stan; Alexandru Mihai Grumezescu; Ecaterina Andronescu; Mariana Carmen Chifiriuc
Journal:  Int J Mol Sci       Date:  2022-07-18       Impact factor: 6.208

2.  Factors associated with mortality in younger and older (≥75 years) hospitalized patients with community-acquired pneumonia.

Authors:  Mehtap Aydin; Bengü Şaylan; İnşa Gül Ekiz İşcanlı
Journal:  Ann Saudi Med       Date:  2022-02-03       Impact factor: 1.526

  2 in total

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