Literature DB >> 33585378

Development and Implementation of Liposomal Encapsulated Micronutrient Fortified Body Oil Intervention for Infant Massage: An Innovative Concept to Prevent Micronutrient Deficiencies in Children.

Aditi Apte1,2, Himangi Lubree1, Mudra Kapoor2, Sanjay Juvekar1, Rinti Banerjee2, Ashish Bavdekar1.   

Abstract

Indian communities have the ancient cultural practice of gentle oil massage for infants which has been shown to play a beneficial role in neuro-motor development. The concept of incorporating nanosized liposomes of micronutrients (i.e., iron, folate, vitamin B12, and vitamin D) in the body oil leverages this practice for transdermal supplementation of essential micro-nutrients. This paper describes the experience of developing an intervention in the form of body oil containing nanosized liposomes of iron and micro-nutrients built on the social context of infant oil massage using a theory of change approach. The process of development of the intervention has been covered into stages such as design, decide and implement. The design phase describes how the idea of nanosized liposomal encapsulated micronutrient fortified (LMF) body oil was conceptualized and how its feasibility was assessed through initial formative work in the community. The decide phase describes steps involved while scaling up technology from laboratory to community level. The implementation phase describes processes while implementing the intervention of LMF oil in a community-based randomized controlled study. Overall, the theory of change approach helps to outline the various intermediate steps and challenges while translating novel technologies for transdermal nutrient fortification to community level. In our experience, adaptation in the technology for large scale up, formative work and pilot testing of innovation at community level were important processes that helped in shaping the innovation. Meticulous mapping of these processes and experiences can be a useful guide for translating similar innovations.
Copyright © 2021 Apte, Lubree, Kapoor, Juvekar, Banerjee and Bavdekar.

Entities:  

Keywords:  causal pathway; implementation science; scale–up; theory of change; translational

Year:  2021        PMID: 33585378      PMCID: PMC7874153          DOI: 10.3389/fpubh.2020.567689

Source DB:  PubMed          Journal:  Front Public Health        ISSN: 2296-2565


  25 in total

1.  Topically applied sunflower seed oil prevents invasive bacterial infections in preterm infants in Egypt: a randomized, controlled clinical trial.

Authors:  Gary L Darmstadt; Nadia Badrawi; Paul A Law; Saifuddin Ahmed; Moataza Bashir; Iman Iskander; Dalia Al Said; Amani El Kholy; Mohamed Hassan Husein; Asif Alam; Peter J Winch; Reginald Gipson; Muhammad Santosham
Journal:  Pediatr Infect Dis J       Date:  2004-08       Impact factor: 2.129

2.  Conclusions of a WHO Technical Consultation on folate and vitamin B12 deficiencies.

Authors:  Bruno de Benoist
Journal:  Food Nutr Bull       Date:  2008-06       Impact factor: 2.069

3.  Rapidly Dissolving Microneedle Patches for Transdermal Iron Replenishment Therapy.

Authors:  Abhijeet Maurya; Shivakumar H Nanjappa; Swati Honnavar; M Salwa; S Narasimha Murthy
Journal:  J Pharm Sci       Date:  2018-02-17       Impact factor: 3.534

4.  Traditional massage of newborns in Nepal: implications for trials of improved practice.

Authors:  Luke C Mullany; Gary L Darmstadt; Subarna K Khatry; James M Tielsch
Journal:  J Trop Pediatr       Date:  2005-01-26       Impact factor: 1.165

5.  Selling Sprinkles micronutrient powder reduces anemia, iron deficiency, and vitamin A deficiency in young children in Western Kenya: a cluster-randomized controlled trial.

Authors:  Parminder S Suchdev; Laird J Ruth; Bradley A Woodruff; Charles Mbakaya; Usha Mandava; Rafael Flores-Ayala; Maria Elena D Jefferds; Robert Quick
Journal:  Am J Clin Nutr       Date:  2012-04-04       Impact factor: 7.045

6.  Traditional practice of oil massage of neonates in Bangladesh.

Authors:  Gary L Darmstadt; Samir K Saha
Journal:  J Health Popul Nutr       Date:  2002-06       Impact factor: 2.000

7.  Preparation and characterization of curcumin-piperine dual drug loaded nanoparticles.

Authors:  C Moorthi; Kiran Krishnan; R Manavalan; K Kathiresan
Journal:  Asian Pac J Trop Biomed       Date:  2012-11

8.  Microporation and 'iron'tophoresis for treating iron deficiency anemia.

Authors:  Naresh Modepalli; Seongbong Jo; Michael A Repka; S Narasimha Murthy
Journal:  Pharm Res       Date:  2012-11-28       Impact factor: 4.200

Review 9.  A Review of the Structure, Preparation, and Application of NLCs, PNPs, and PLNs.

Authors:  Qianwen Li; Tiange Cai; Yinghong Huang; Xi Xia; Susan P C Cole; Yu Cai
Journal:  Nanomaterials (Basel)       Date:  2017-05-27       Impact factor: 5.076

Review 10.  Nano based drug delivery systems: recent developments and future prospects.

Authors:  Jayanta Kumar Patra; Gitishree Das; Leonardo Fernandes Fraceto; Estefania Vangelie Ramos Campos; Maria Del Pilar Rodriguez-Torres; Laura Susana Acosta-Torres; Luis Armando Diaz-Torres; Renato Grillo; Mallappa Kumara Swamy; Shivesh Sharma; Solomon Habtemariam; Han-Seung Shin
Journal:  J Nanobiotechnology       Date:  2018-09-19       Impact factor: 10.435

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