Literature DB >> 33585266

The Role of Porphyromonas gingivalis Outer Membrane Vesicles in Periodontal Disease and Related Systemic Diseases.

Zhiying Zhang1, Dongjuan Liu2, Sai Liu3, Shuwei Zhang1, Yaping Pan1.   

Abstract

Periodontal disease is a chronic infectious disease associated with a variety of bacteria, which can cause damage to the periodontal support structure and affect a variety of systemic system diseases such as cancer, cardiovascular disease, diabetes, rheumatoid arthritis, non-alcoholic fatty liver, and Alzheimer's disease. Porphyromonas gingivalis (P. gingivalis) is the most important pathogenic bacteria for periodontal disease. It can produce outer membrane vesicles (OMVs) and release them into the environment, playing an important role in its pathogenesis. This article focuses on P. gingivalis OMVs, reviews its production and regulation, virulence components, mode of action and related diseases, with a view to providing new ideas for the prevention and treatment of diseases related to P. gingivalis infections.
Copyright © 2021 Zhang, Liu, Liu, Zhang and Pan.

Entities:  

Keywords:  Porphyromonas gingivalis; outer membrane vesicles; periodontal disease; systemic diseases; virulence factors

Year:  2021        PMID： 33585266      PMCID： PMC7877337          DOI： 10.3389/fcimb.2020.585917

Source DB:  PubMed          Journal:  Front Cell Infect Microbiol        ISSN： 2235-2988            Impact factor:   5.293


  102 in total

Review 1.  Virulence and immunomodulatory roles of bacterial outer membrane vesicles.

Authors:  Terri N Ellis; Meta J Kuehn
Journal:  Microbiol Mol Biol Rev       Date:  2010-03       Impact factor: 11.056

2.  Implantation of Bacteroides gingivalis in nonhuman primates initiates progression of periodontitis.

Authors:  S C Holt; J Ebersole; J Felton; M Brunsvold; K S Kornman
Journal:  Science       Date:  1988-01-01       Impact factor: 47.728

3.  Porphyromonas gingivalis vesicles enhance attachment, and the leucine-rich repeat BspA protein is required for invasion of epithelial cells by "Tannerella forsythia".

Authors:  Satoru Inagaki; Shinsuke Onishi; Howard K Kuramitsu; Ashu Sharma
Journal:  Infect Immun       Date:  2006-09       Impact factor: 3.441

4.  Association between interleukin-1 genotype and periodontal disease in a diabetic population.

Authors:  Sergio Guzman; Mamdouh Karima; Hwa-Ying Wang; Thomas E Van Dyke
Journal:  J Periodontol       Date:  2003-08       Impact factor: 6.993

5.  Inflammatory responses of gingival epithelial cells stimulated with Porphyromonas gingivalis vesicles are inhibited by hop-associated polyphenols.

Authors:  Yurong Kou; Hiroaki Inaba; Takahiro Kato; Motoyuki Tagashira; Daiki Honma; Tomomasa Kanda; Yasuyuki Ohtake; Atsuo Amano
Journal:  J Periodontol       Date:  2008-01       Impact factor: 6.993

6.  Porphyromonas gingivalis RgpA-Kgp proteinase-adhesin complexes penetrate gingival tissue and induce proinflammatory cytokines or apoptosis in a concentration-dependent manner.

Authors:  Neil M O'Brien-Simpson; Rishi D Pathirana; Glenn D Walker; Eric C Reynolds
Journal:  Infect Immun       Date:  2008-12-29       Impact factor: 3.441

7.  Outer membrane vesicles of Porphyromonas gingivalis attenuate insulin sensitivity by delivering gingipains to the liver.

Authors:  Mariko Seyama; Kaya Yoshida; Kayo Yoshida; Natsumi Fujiwara; Kisho Ono; Takanori Eguchi; Hotaka Kawai; Jiajie Guo; Yao Weng; Yuan Haoze; Kenta Uchibe; Mika Ikegame; Akira Sasaki; Hitoshi Nagatsuka; Kuniaki Okamoto; Hirohiko Okamura; Kazumi Ozaki
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2020-02-20       Impact factor: 5.187

8.  Outer membrane vesicles of Porphyromonas gingivalis elicit a mucosal immune response.

Authors:  Ryoma Nakao; Hideki Hasegawa; Kuniyasu Ochiai; Shogo Takashiba; Akira Ainai; Makoto Ohnishi; Haruo Watanabe; Hidenobu Senpuku
Journal:  PLoS One       Date:  2011-10-14       Impact factor: 3.240

9.  Diabetes Activates Periodontal Ligament Fibroblasts via NF-κB In Vivo.

Authors:  J Zheng; S Chen; M L Albiero; G H A Vieira; J Wang; J Q Feng; D T Graves
Journal:  J Dent Res       Date:  2018-02-13       Impact factor: 8.924

Review 10.  Could early rheumatoid arthritis resolve after periodontitis treatment only?: case report and review of the literature.

Authors:  Simonetta Salemi; Michela I Biondo; Chiara Fiorentino; Giuseppe Argento; Michele Paolantonio; Carlo Di Murro; Vito A Malagnino; Marco Canzoni; Andrea Picchianti Diamanti; Raffaele D'Amelio
Journal:  Medicine (Baltimore)       Date:  2014-12       Impact factor: 1.889
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  16 in total

Review 1.  Peridontitis as a Risk Factor for Attention Deficit Hyperactivity Disorder: Possible Neuro-inflammatory Mechanisms.

Authors:  Samson K Wilson; Jaya Thomas
Journal:  Neurochem Res       Date:  2022-06-28       Impact factor: 4.414

2.  Atypical cyclic di-AMP signaling is essential for Porphyromonas gingivalis growth and regulation of cell envelope homeostasis and virulence.

Authors:  M Fata Moradali; Shirin Ghods; Heike Bähre; Richard J Lamont; David A Scott; Roland Seifert
Journal:  NPJ Biofilms Microbiomes       Date:  2022-07-06       Impact factor: 8.462

Review 3.  The Microbiome in Pancreatic Cancer-Implications for Diagnosis and Precision Bacteriophage Therapy for This Low Survival Disease.

Authors:  Mwila Kabwe; Stuart Dashper; Joseph Tucci
Journal:  Front Cell Infect Microbiol       Date:  2022-05-19       Impact factor: 6.073

Review 4.  Protein Tyrosine and Serine/Threonine Phosphorylation in Oral Bacterial Dysbiosis and Bacteria-Host Interaction.

Authors:  Liang Ren; Daonan Shen; Chengcheng Liu; Yi Ding
Journal:  Front Cell Infect Microbiol       Date:  2022-01-11       Impact factor: 5.293

Review 5.  Leaky Gum: The Revisited Origin of Systemic Diseases.

Authors:  Do-Young Park; Jin Young Park; Dahye Lee; Inseong Hwang; Hye-Sung Kim
Journal:  Cells       Date:  2022-03-23       Impact factor: 6.600

Review 6.  Oral and Gut Microbial Dysbiosis and Non-alcoholic Fatty Liver Disease: The Central Role of Porphyromonas gingivalis.

Authors:  Ting Wang; Taichi Ishikawa; Minoru Sasaki; Toshimi Chiba
Journal:  Front Med (Lausanne)       Date:  2022-03-02

Review 7.  The Role of Extracellular Vesicles as a Shared Disease Mechanism Contributing to Multimorbidity in Patients With COPD.

Authors:  Laura V Reid; C Mirella Spalluto; Alastair Watson; Karl J Staples; Tom M A Wilkinson
Journal:  Front Immunol       Date:  2021-12-02       Impact factor: 7.561

Review 8.  Delivery of Toxins and Effectors by Bacterial Membrane Vesicles.

Authors:  Adrian Macion; Agnieszka Wyszyńska; Renata Godlewska
Journal:  Toxins (Basel)       Date:  2021-11-26       Impact factor: 4.546

9.  Tetrahydroimidazo[4,5-c]pyridine-Based Inhibitors of Porphyromonas gingivalis Glutaminyl Cyclase.

Authors:  Daniel Ramsbeck; Nadine Taudte; Nadine Jänckel; Stefanie Strich; Jens-Ulrich Rahfeld; Mirko Buchholz
Journal:  Pharmaceuticals (Basel)       Date:  2021-11-23

10.  Poor oral health and risks of total and site-specific cancers in China: A prospective cohort study of 0.5 million adults.

Authors:  Xi Zhang; Ben Liu; Henry S Lynn; Kexin Chen; Hongji Dai
Journal:  EClinicalMedicine       Date:  2022-03-05
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