Literature DB >> 33585120

Signet-Ring Cell Colon Cancer in a Teenager: A Case Report.

Amy Somerset1,2, David A Edelman2, John Webber2.   

Abstract

The majority of colon cancers are diagnosed in the older population, though recent trends have demonstrated an increase in younger patients. Most colon cancers are considered adenocarcinoma. There are multiple histologic subtypes with varying prognoses. Mucinous types such as signet-ring cell carcinoma (SRCC) are more aggressive with poor outcomes. SRCC frequently presents with metastatic disease which contributes to its poor prognosis. It is most commonly diagnosed around age 40. SRCC of colonic origin is very rare and comprises only 1% of colorectal cancers. Rarer still is presentation in the teenaged patient, especially in the absence of any risk factors. We present a case of an 18-year-old male with colonic SRCC. The patient presented initially with vague abdominal discomfort and three weeks later was found to have a near-obstructing right-sided colon mass. He was taken to the operating room and found to have diffuse carcinomatosis. The patient underwent palliative loop ileostomy with plans for subsequent chemotherapy.
Copyright © 2021, Somerset et al.

Entities:  

Keywords:  colorectal cancer; metastatic colo-rectal cancer; signet ring cell adenocarcinoma; teenage

Year:  2021        PMID: 33585120      PMCID: PMC7872477          DOI: 10.7759/cureus.12632

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  4 in total

Review 1.  Outcomes of surgical treatment of primary signet ring cell carcinoma of the colon and rectum: 22 cases reviewed with literature.

Authors:  Sedat Belli; Huseyin Ozgur Aytac; Erdal Karagulle; Hakan Yabanoglu; Fazilet Kayaselcuk; Sedat Yildirim
Journal:  Int Surg       Date:  2014 Nov-Dec

2.  Increasing disparities in the age-related incidences of colon and rectal cancers in the United States, 1975-2010.

Authors:  Christina E Bailey; Chung-Yuan Hu; Y Nancy You; Brian K Bednarski; Miguel A Rodriguez-Bigas; John M Skibber; Scott B Cantor; George J Chang
Journal:  JAMA Surg       Date:  2015-01       Impact factor: 14.766

3.  Young-onset colorectal cancer in patients with no known genetic predisposition: can we increase early recognition and improve outcome?

Authors:  Eric J Dozois; Lisa A Boardman; Weerapat Suwanthanma; Paul J Limburg; Robert R Cima; Julie L Bakken; Robert A Vierkant; Jeremiah A Aakre; David W Larson
Journal:  Medicine (Baltimore)       Date:  2008-09       Impact factor: 1.889

4.  Early-Onset Signet-Ring Cell Adenocarcinoma of the Colon: A Case Report and Review of the Literature.

Authors:  Maliha Khan; Krittiya Korphaisarn; Aneeqa Saif; Wai C Foo; Scott Kopetz
Journal:  Case Rep Oncol Med       Date:  2017-02-23
  4 in total

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