MULTI-SHOT SENSITIVITY-ENCODED DIFFUSION MRI USING MODEL-BASED DEEP LEARNING (MODL-MUSSELS).

We propose a model-based deep learning architecture for the correction of phase errors in multishot diffusion-weighted echo-planar MRI images. This work is a generalization of MUSSELS, which is a structured low-rank algorithm. We show that an iterative reweighted least-squares implementation of MUSSELS resembles the model-based deep learning (MoDL) framework. We propose to replace the self-learned linear filter bank in MUSSELS with a convolutional neural network, whose parameters are learned from exemplary data. The proposed algorithm reduces the computational complexity of MUSSELS by several orders of magnitude, while providing comparable image quality.