Literature DB >> 33584956

Recurrent Plaque Morphea Successfully Treated with PDO Mono Threads and Topical Tacrolimus Ointment.

Jagdish Sakhiya1, Dhruv Sakhiya1, Ashish Dedakiya1, Madhav Purohit1, Mihir Modi1, Piyush Darji1, Feral Daruwala1, Nimish Dudhatra1.   

Abstract

The term plaque morphea describes a variant of morphea (localized scleroderma) in which oval or round circumscribed areas of induration, pigmentary changes, and violaceous or erythematous halo (i.e., lilac ring) are found in the dermis and occasionally to the superficial panniculus. We report a case of 28-year-old male patient with recurrent plaque morphea who was treated with polydioxanone (PDO) mono threads and topical tacrolimus ointment. After the introduction of PDO mono threads, the patient was prescribed topical tacrolimus ointment for six months. After that six-month period, the lesions were softer to palpation and lighter in color. This was observed as a positive therapeutic response. Notably, no future recurrence was seen at one-year follow up.
Copyright © 2020. Matrix Medical Communications. All rights reserved.

Entities:  

Keywords:  PDO mono thread; morphea; morphea en plaque; tacrolimus ointment

Year:  2020        PMID: 33584956      PMCID: PMC7840089     

Source DB:  PubMed          Journal:  J Clin Aesthet Dermatol        ISSN: 1941-2789


  15 in total

1.  Guess what? Inflammatory disseminated morphea profunda.

Authors:  P Savoia; A Zaccagna; M G Bernengo
Journal:  Eur J Dermatol       Date:  1999-12       Impact factor: 3.328

Review 2.  Systemic manifestations in localized scleroderma.

Authors:  Francesco Zulian
Journal:  Curr Rheumatol Rep       Date:  2004-12       Impact factor: 4.592

3.  First case series on the use of imiquimod for morphoea.

Authors:  M Dytoc; P T Ting; J Man; D Sawyer; L Fiorillo
Journal:  Br J Dermatol       Date:  2005-10       Impact factor: 9.302

Review 4.  Update on morphea: part I. Epidemiology, clinical presentation, and pathogenesis.

Authors:  Nicole Fett; Victoria P Werth
Journal:  J Am Acad Dermatol       Date:  2011-02       Impact factor: 11.527

Review 5.  Localized scleroderma.

Authors:  Ronald M Laxer; Francesco Zulian
Journal:  Curr Opin Rheumatol       Date:  2006-11       Impact factor: 5.006

Review 6.  Classification of morphea (localized scleroderma)

Authors:  L S Peterson; A M Nelson; W P Su
Journal:  Mayo Clin Proc       Date:  1995-11       Impact factor: 7.616

7.  Topical calcipotriene for morphea/linear scleroderma.

Authors:  B B Cunningham; I D Landells; C Langman; D E Sailer; A S Paller
Journal:  J Am Acad Dermatol       Date:  1998-08       Impact factor: 11.527

8.  Distinct autoimmune syndromes in morphea: a review of 245 adult and pediatric cases.

Authors:  Justin J Leitenberger; Rachael L Cayce; Robert W Haley; Beverley Adams-Huet; Paul R Bergstresser; Heidi T Jacobe
Journal:  Arch Dermatol       Date:  2009-05

9.  The role of skin trauma in the distribution of morphea lesions: a cross-sectional survey of the Morphea in Adults and Children cohort IV.

Authors:  Daniel Grabell; Clifford Hsieh; Rachel Andrew; Kathryn Martires; Andrew Kim; Rebecca Vasquez; Heidi Jacobe
Journal:  J Am Acad Dermatol       Date:  2014-05-28       Impact factor: 11.527

Review 10.  Pathogenesis and therapeutic approaches for improved topical treatment in localized scleroderma and systemic sclerosis.

Authors:  I Badea; M Taylor; A Rosenberg; M Foldvari
Journal:  Rheumatology (Oxford)       Date:  2008-11-20       Impact factor: 7.580

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