Literature DB >> 33580176

Evaluation of the usefulness of saliva for mosaic loss of chromosome Y analysis.

Tsuyoshi Hachiya1, Takuro Kobayashi2, Wataru Tsutae3, Pamela Hui Peng Gan3, Iri Sato Baran3, Shigeo Horie4,5.   

Abstract

Mosaic loss of chromosome Y (mLOY) in leukocytes has attracted much attention as an emerging biomarker of aging and aging-related diseases. We evaluated the usefulness of saliva for mLOY analysis and showed that saliva-derived mLOY is significantly associated with aging and increased physical activity, but not with smoking. While these data support the robust association between saliva-derived mLOY and aging, caution is required when comparing data from saliva-derived and blood-derived mLOY.

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Year:  2021        PMID： 33580176      PMCID： PMC7881200          DOI： 10.1038/s41598-021-83308-8

Source DB:  PubMed          Journal:  Sci Rep        ISSN： 2045-2322            Impact factor:   4.379


  23 in total

1.  Change of human chromosome count distribution with age: evidence for a sex differences.

Authors:  P A JACOBS; M BRUNTON; W M COURT BROWN; R DOLL; H GOLDSTEIN
Journal:  Nature       Date:  1963-03-16       Impact factor: 49.962

2.  Prevention, diagnosis, and treatment of the overtraining syndrome: joint consensus statement of the European College of Sport Science and the American College of Sports Medicine.

Authors:  Romain Meeusen; Martine Duclos; Carl Foster; Andrew Fry; Michael Gleeson; David Nieman; John Raglin; Gerard Rietjens; Jürgen Steinacker; Axel Urhausen
Journal:  Med Sci Sports Exerc       Date:  2013-01       Impact factor: 5.411

3.  The effect of physical activity on mortality and cardiovascular disease in 130 000 people from 17 high-income, middle-income, and low-income countries: the PURE study.

Authors:  Scott A Lear; Weihong Hu; Sumathy Rangarajan; Danijela Gasevic; Darryl Leong; Romaina Iqbal; Amparo Casanova; Sumathi Swaminathan; R M Anjana; Rajesh Kumar; Annika Rosengren; Li Wei; Wang Yang; Wang Chuangshi; Liu Huaxing; Sanjeev Nair; Rafael Diaz; Hany Swidon; Rajeev Gupta; Noushin Mohammadifard; Patricio Lopez-Jaramillo; Aytekin Oguz; Katarzyna Zatonska; Pamela Seron; Alvaro Avezum; Paul Poirier; Koon Teo; Salim Yusuf
Journal:  Lancet       Date:  2017-09-21       Impact factor: 79.321

Review 4.  Detectable clonal mosaicism in the human genome.

Authors:  Mitchell J Machiela; Stephen J Chanock
Journal:  Semin Hematol       Date:  2013-10       Impact factor: 3.851

5.  Mosaic Y Loss Is Moderately Associated with Solid Tumor Risk.

Authors:  Erikka Loftfield; Weiyin Zhou; Meredith Yeager; Stephen J Chanock; Neal D Freedman; Mitchell J Machiela
Journal:  Cancer Res       Date:  2018-12-03       Impact factor: 12.701

6.  The utility of DNA extracted from saliva for genome-wide molecular research platforms.

Authors:  Fiona J Bruinsma; Jihoon E Joo; Ee Ming Wong; Graham G Giles; Melissa C Southey
Journal:  BMC Res Notes       Date:  2018-01-08

7.  Genetic predisposition to mosaic Y chromosome loss in blood.

Authors:  Lars A Forsberg; John R B Perry; Deborah J Thompson; Giulio Genovese; Jonatan Halvardson; Jacob C Ulirsch; Daniel J Wright; Chikashi Terao; Olafur B Davidsson; Felix R Day; Patrick Sulem; Yunxuan Jiang; Marcus Danielsson; Hanna Davies; Joe Dennis; Malcolm G Dunlop; Douglas F Easton; Victoria A Fisher; Florian Zink; Richard S Houlston; Martin Ingelsson; Siddhartha Kar; Nicola D Kerrison; Ben Kinnersley; Ragnar P Kristjansson; Philip J Law; Rong Li; Chey Loveday; Jonas Mattisson; Steven A McCarroll; Yoshinori Murakami; Anna Murray; Pawel Olszewski; Edyta Rychlicka-Buniowska; Robert A Scott; Unnur Thorsteinsdottir; Ian Tomlinson; Behrooz Torabi Moghadam; Clare Turnbull; Nicholas J Wareham; Daniel F Gudbjartsson; Yoichiro Kamatani; Eva R Hoffmann; Steve P Jackson; Kari Stefansson; Adam Auton; Ken K Ong; Mitchell J Machiela; Po-Ru Loh; Jan P Dumanski; Stephen J Chanock
Journal:  Nature       Date:  2019-11-20       Impact factor: 49.962

Review 8.  Hypogonadism in Exercising Males: Dysfunction or Adaptive-Regulatory Adjustment?

Authors:  Anthony C Hackney
Journal:  Front Endocrinol (Lausanne)       Date:  2020-01-31       Impact factor: 5.555

9.  Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer.

Authors:  Lars A Forsberg; Chiara Rasi; Niklas Malmqvist; Hanna Davies; Saichand Pasupulati; Geeta Pakalapati; Johanna Sandgren; Teresita Diaz de Ståhl; Ammar Zaghlool; Vilmantas Giedraitis; Lars Lannfelt; Joannah Score; Nicholas C P Cross; Devin Absher; Eva Tiensuu Janson; Cecilia M Lindgren; Andrew P Morris; Erik Ingelsson; Lars Lind; Jan P Dumanski
Journal:  Nat Genet       Date:  2014-04-28       Impact factor: 38.330

10.  The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly.

Authors:  Mark Pinese; Paul Lacaze; Emma M Rath; Andrew Stone; Marie-Jo Brion; Adam Ameur; Sini Nagpal; Clare Puttick; Shane Husson; Dmitry Degrave; Tina Navin Cristina; Vivian F S Kahl; Aaron L Statham; Robyn L Woods; John J McNeil; Moeen Riaz; Margo Barr; Mark R Nelson; Christopher M Reid; Anne M Murray; Raj C Shah; Rory Wolfe; Joshua R Atkins; Chantel Fitzsimmons; Heath M Cairns; Melissa J Green; Vaughan J Carr; Mark J Cowley; Hilda A Pickett; Paul A James; Joseph E Powell; Warren Kaplan; Greg Gibson; Ulf Gyllensten; Murray J Cairns; Martin McNamara; Marcel E Dinger; David M Thomas
Journal:  Nat Commun       Date:  2020-01-23       Impact factor: 14.919
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  1 in total

1.  Rats exhibit age-related mosaic loss of chromosome Y.

Authors:  Alberto H Orta; Stephen J Bush; Mariana Gutiérrez-Mariscal; Susana Castro-Obregón; Lorraine Jaimes-Hoy; Ricardo Grande; Gloria Vázquez; Elisa Gorostieta-Salas; Mónica Martínez-Pacheco; Karina Díaz-Barba; Paola Cornejo-Páramo; Alejandro Sanchez-Flores; Tamas Székely; Araxi O Urrutia; Diego Cortez
Journal:  Commun Biol       Date:  2021-12-21
  1 in total

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