| Literature DB >> 33578780 |
Li Ma1, MengMeng Zhang2, Rong Zhao2, Dan Wang2, YueRong Ma1, Ai Li3.
Abstract
Cancer is a major factor threatening human health and life safety, and there is a lack of safe and effective therapeutic drugs. Intervention and prevention in premalignant process are effective ways to reverse carcinogenesis and prevent cancer from occurring. Plant natural products are rich in sources and are a promising source for cancer chemoprevention. This article reviews the chemopreventive effects of natural products, especially focused on polyphenols, flavonoids, monoterpene and triterpenoids, sulfur compounds, and cellulose. Meanwhile, the main mechanisms include induction of apoptosis, antiproliferation and inhibition of metastasis are briefly summarized. In conclusion, this article provides evidence for natural products remaining a prominent source of cancer chemoprevention.Entities:
Keywords: cancer chemoprevention; natural product; plant
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Year: 2021 PMID: 33578780 PMCID: PMC7916513 DOI: 10.3390/molecules26040933
Source DB: PubMed Journal: Molecules ISSN: 1420-3049 Impact factor: 4.411