Literature DB >> 33578671

A Systematic Review and Meta-Analysis of Wound Complications after a Caesarean Section in Obese Women.

Aneta Słabuszewska-Jóźwiak1, Jacek Krzysztof Szymański1, Łukasz Jóźwiak2, Beata Sarecka-Hujar3.   

Abstract

(1) Background: Caesarean sections in obese patients are associated with an increased risk of surgical wound complications, including hematomas, seromas, abscesses, dehiscence, and surgical site infections. The aim of the present study is to perform a meta-analysis and systematic review of the current literature focusing on the strategies available to decrease wound complications in this population. (2)
Methods: We reviewed the data available from the PubMed and the Science Direct databases concerning wound complications after caesarean sections in obese women. The following key words were used: "caesarean section", "cesarean section", "wound complication", "wound morbidity", and "wound infection". A total of 540 papers were retrieved, 40 of which were selected for the final systematic review and whereas 21 articles provided data for meta-analysis. (3)
Results: The conducted meta-analyses revealed that the use of prophylactic drainage does not increase the risk of wound complications in obese women after a caesarean sections (pooled OR = 1.32; 95% CI 0.64-2.70, p = 0.45) and that vertical skin incisions increase wound complications (pooled OR = 2.48; 95% CI 1.85-3.32, p < 0.01) in obese women, including extremely obese women. (4) Conclusions: Subcutaneous drainage does not reduce the risk of a wound complications, wound infections, and fever in obese women after caesarean sections. Negative prophylactic pressure wound therapy (NPWT) may reduce the risk of surgical site infections. The evidence of using a prophylactic dose of an antibiotic before the caesarean section is still lacking.

Entities:  

Keywords:  caesarean section; surgical-site infection; wound complication; wound infection; wound morbidity

Year:  2021        PMID: 33578671      PMCID: PMC7916387          DOI: 10.3390/jcm10040675

Source DB:  PubMed          Journal:  J Clin Med        ISSN: 2077-0383            Impact factor:   4.241


  65 in total

1.  A combination of subcuticular sutures and a drain for skin closure reduces wound complications in obese women undergoing surgery using vertical incisions.

Authors:  Y Inotsume-Kojima; T Uchida; M Abe; T Doi; N Kanayama
Journal:  J Hosp Infect       Date:  2010-10-23       Impact factor: 3.926

2.  Subcutaneous stitch closure versus subcutaneous drain to prevent wound disruption after cesarean delivery: a randomized clinical trial.

Authors:  Everett F Magann; Suneet P Chauhan; Sheryl Rodts-Palenik; Laura Bufkin; James N Martin; John C Morrison
Journal:  Am J Obstet Gynecol       Date:  2002-06       Impact factor: 8.661

Review 3.  Prophylactic subcutaneous drainage for prevention of wound complications after cesarean delivery--a metaanalysis.

Authors:  Elizabeth K Hellums; Monique G Lin; Patrick S Ramsey
Journal:  Am J Obstet Gynecol       Date:  2007-09       Impact factor: 8.661

4.  Cefazolin prophylaxis in obese women undergoing cesarean delivery: a randomized controlled trial.

Authors:  Lindsay Maggio; David P Nicolau; Melissa DaCosta; Dwight J Rouse; Brenna L Hughes
Journal:  Obstet Gynecol       Date:  2015-05       Impact factor: 7.661

Review 5.  Prophylactic negative-pressure wound therapy after cesarean is associated with reduced risk of surgical site infection: a systematic review and meta-analysis.

Authors:  Lulu Yu; Ryan J Kronen; Laura E Simon; Carolyn R T Stoll; Graham A Colditz; Methodius G Tuuli
Journal:  Am J Obstet Gynecol       Date:  2017-09-23       Impact factor: 8.661

6.  A survey of caesarean section surgical site infections with PICO™ Single Use Negative Pressure Wound Therapy System in high-risk patients in England and Ireland.

Authors:  R J Searle; D Myers
Journal:  J Hosp Infect       Date:  2017-08-12       Impact factor: 3.926

7.  Does current cefazolin dosing achieve adequate tissue and blood concentrations in obese women undergoing cesarean section?

Authors:  Jessica J F Kram; Danielle M Greer; Omar Cabrera; Robert Burlage; Marie M Forgie; Danish S Siddiqui
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2017-01-19       Impact factor: 2.435

8.  Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials.

Authors:  Jonathan A C Sterne; Alex J Sutton; John P A Ioannidis; Norma Terrin; David R Jones; Joseph Lau; James Carpenter; Gerta Rücker; Roger M Harbord; Christopher H Schmid; Jennifer Tetzlaff; Jonathan J Deeks; Jaime Peters; Petra Macaskill; Guido Schwarzer; Sue Duval; Douglas G Altman; David Moher; Julian P T Higgins
Journal:  BMJ       Date:  2011-07-22

9.  Closed Incision Negative Pressure Therapy in Morbidly Obese Women Undergoing Cesarean Delivery: A Randomized Controlled Trial.

Authors:  Deana J Hussamy; Alison C Wortman; Donald D McIntire; Kenneth J Leveno; Brian M Casey; Scott W Roberts
Journal:  Obstet Gynecol       Date:  2019-10       Impact factor: 7.661

10.  Obstetric Surgical Site Infections: 2 Grams Compared With 3 Grams of Cefazolin in Morbidly Obese Women.

Authors:  Homa K Ahmadzia; Emily M Patel; Dipa Joshi; Caiyun Liao; Frank Witter; R Phillips Heine; Jenell S Coleman
Journal:  Obstet Gynecol       Date:  2015-10       Impact factor: 7.661

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