Literature DB >> 33577946

Patient-Selected Treatment Goals in Severe Asthma.

Christopher Mulvey1, Elaine MacHale2, Garrett Greene2, Lorna Lombard2, Joanne Walsh2, Sinead Plunkett2, Thomas A McCartan2, Vincent Brennan2, Fiona O'Hannigan2, Matshediso Mokoka2, Richard W Costello2.   

Abstract

BACKGROUND: Goal-orientated health care accounts for patient preferences and values, not just physician treatment aims. The Global Initiative for Asthma (GINA) management strategy states that clinicians should elicit patients' own treatment goals as a central part of care. Despite this recommendation, data on patients' treatment goals are sparse among patients with severe asthma.
OBJECTIVE: The objective of this study is to investigate the relationship between rates of treatment adherence and goal achievement, and patient-selected goals.
METHODS: Thematic analysis was used to characterize patient-selected goals. Previously undescribed goal categories in asthma were identified, quantified, and related to clinical characteristics. Goal achievement was aligned with objectively measured treatment adherence.
RESULTS: Three categories of patients-selected goals were identified from 2 randomized control trials: disease-specific (n = 98 [51%] and n = 92 [54%], respectively), function-related (n = 90 [48%] and n = 61 [36%]), and knowledge (n = 1 [1%] and n = 17 [10%]). Only 53% of goals aligned with clinician treatment goals. Patients who chose disease-specific goals were more likely to achieve both control and their specified goal (n = 98 [45%], odds ratio: 1.789, confidence interval: 1.066-3.001). Male participants are more likely to focus on disease-specific goals. Patients who achieved their goals were more likely to be T2-high, have an elevated fractional exhaled nitric oxide (FeNO) at their first visit, and have a lower FeNO value at their final visit. Interestingly, adherence rates decline significantly for those who achieve their goals.
CONCLUSION: Almost half of patient-selected goals do not align with GINA clinical asthma management goals. Participants who chose goals that do align with clinicians were more likely to achieve them.
Copyright © 2021 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Adherence; Asthma; Inhaler education; Inhaler technique; Patient goals; Respiratory; Treatment goals

Year:  2021        PMID: 33577946     DOI: 10.1016/j.jaip.2021.01.041

Source DB:  PubMed          Journal:  J Allergy Clin Immunol Pract


  2 in total

Review 1.  The clinical impact of adherence to therapy in airways disease.

Authors:  Vincent Brennan; Christopher Mulvey; Richard W Costello
Journal:  Breathe (Sheff)       Date:  2021-06

2.  A Clinical Perspective on the Role of Electronic Devices in Monitoring and Promoting Adherence in Airways Disease.

Authors:  Vincent Brennan; Christopher Mulvey; Garrett Greene; Elaine Mac Hale; Richard W Costello
Journal:  Front Med Technol       Date:  2021-04-12
  2 in total

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