Gaël Le Roux1, Sandra Sinno-Tellier2, Emmanuel Puskarczyk3, Magali Labadie4, Katharina von Fabeck5, Fanny Pélissier6, Patrick Nisse7, Nathalie Paret8, Alexis Descatha1,9, Dominique Vodovar10,11,12. 1. Centre antipoison et de Toxicovigilance Grand Ouest, CHU Angers, Angers Cedex 9, France. 2. Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Maisons-Alfort Cedex, France. 3. Centre antipoison et de Toxicovigilance Grand Est et Base Nationale Produits et Compositions, CHRU de Nancy, Nancy Cedex, France. 4. Centre antipoison et de Toxicovigilance de Bordeaux, CHU Pellegrin Tripode, Place Amélie Raba Léon, Bordeaux Cedex, France. 5. Centre antipoison et de Toxicovigilance de Marseille, Hôpital Sainte Marguerite, Marseille Cedex 09, France. 6. Centre Antipoison et de Toxicovigilance de Toulouse, Hôpital Purpan, Pavillon Louis Lareng, Toulouse Cedex, France. 7. Centre antipoison et de Toxicovigilance de Lille, CHU de Lille, Lille Cedex, France. 8. Centre antipoison et de Toxicovigilance de Lyon, Hospices Civils de Lyon, Lyon Cedex 03, France. 9. UNIV Angers, CHU Angers, Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S1085, Angers, France. 10. Centre antipoison et de Toxicovigilance de Paris, Assistance Publique des Hôpitaux de Paris - Hôpital Fernand Widal, Paris, France. 11. Université de Paris, UFR de médecine, Paris, France. 12. Faculté de Pharmacie de Paris, INSERM UMRS 1144, Paris, France.
Abstract
INTRODUCTION: The aim was to assess the impact of the COVID-19 pandemic on French Poison Control Centre (PCC) call characteristics. METHODS: Reported cases of xenobiotic exposures from 1 March to 30 April in 2018, 2019, and 2020 were extracted from the French National Database of Poisonings. The collected data included call, patient, and exposure characteristics for both general calls and for calls involving sentinel xenobiotic categories related to the COVID-19 pandemic. The 2020 exposures were compared to 2018-2019 exposures by using simple logistic models in order to provide effect size with odds ratios. RESULTS: From March to April 2020, 32,182 exposures were reported to French PCCs with an overall increase of 5.6% compared to exposures in the same time frame in 2018-2019. A similar increase in calls was observed in non-epidemic and epidemic COVID-19 areas with an increase in calls from the public (+13.6%) while calls from health-professionals decreased (-7.5%). Despite the increase in exposures, the incidence of symptomatic exposures remained stable (-0.4%) with a decrease in severity (moderate/severe -17.2%). A significant increase in exposures to home cleaning products containing biocides, essential oils, and alcohol-based hand sanitizers (odds ratio >1.3, p < .0001) was observed. DISCUSSION AND CONCLUSION: The COVID-19 pandemic altered calls to French PCCs with a small increase in calls during the study period and changes in the pattern of exposure. These changes possibly reflected the indirect consequences of the COVID-19 pandemic i.e., limited access to primary care, fear of contracting COVID-19 and anxiety related to home isolation.
INTRODUCTION: The aim was to assess the impact of the COVID-19 pandemic on French Poison Control Centre (PCC) call characteristics. METHODS: Reported cases of xenobiotic exposures from 1 March to 30 April in 2018, 2019, and 2020 were extracted from the French National Database of Poisonings. The collected data included call, patient, and exposure characteristics for both general calls and for calls involving sentinel xenobiotic categories related to the COVID-19 pandemic. The 2020 exposures were compared to 2018-2019 exposures by using simple logistic models in order to provide effect size with odds ratios. RESULTS: From March to April 2020, 32,182 exposures were reported to French PCCs with an overall increase of 5.6% compared to exposures in the same time frame in 2018-2019. A similar increase in calls was observed in non-epidemic and epidemic COVID-19 areas with an increase in calls from the public (+13.6%) while calls from health-professionals decreased (-7.5%). Despite the increase in exposures, the incidence of symptomatic exposures remained stable (-0.4%) with a decrease in severity (moderate/severe -17.2%). A significant increase in exposures to home cleaning products containing biocides, essential oils, and alcohol-based hand sanitizers (odds ratio >1.3, p < .0001) was observed. DISCUSSION AND CONCLUSION: The COVID-19 pandemic altered calls to French PCCs with a small increase in calls during the study period and changes in the pattern of exposure. These changes possibly reflected the indirect consequences of the COVID-19 pandemic i.e., limited access to primary care, fear of contracting COVID-19 and anxiety related to home isolation.
Entities:
Keywords:
COVID-19; alcohol-based hand sanitizers; bleach; disinfectants; essential oil
Authors: Liqaa Raffee; Hamza M Daradkeh; Khaled Alawneh; Aida I Al-Fwadleh; Moath Darweesh; Nouran H Hammad; Sami A Almasarweh Journal: BMJ Open Date: 2021-12-09 Impact factor: 2.692
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