Literature DB >> 33576065

Half of all hospitalised children treated with antibiotics for pneumonia did not fulfil radiological, microbiological or laboratory criteria.

Maren Selvåg1, Christian Magnus Thaulow1,2.   

Abstract

AIM: Evaluating the management of paediatric pneumonia is important. We aimed to estimate the proportion of children receiving antibiotics for suspected community-acquired pneumonia (CAP) that were likely to have a bacterial infection. Furthermore, we described antibiotic use in relation to guidelines.
METHODS: We conducted a prospective observational study from a paediatric department in Norway. During 2017, all admitted children aged 0-17 years receiving antibiotics for CAP were enrolled in the study. We collected relevant data and defined likely CAP as one or more of the following: radiologically confirmed pneumonia, c-reactive protein of at least 100 mg/L, positive bacterial culture from blood or pleura, detection of bacteria from the nasopharynx associated with atypical pneumonia.
RESULTS: In total, 70 episodes of suspected CAP were included. Median age was 41.5 months, and 36 (51%) were girls. Of all treatments, 38 (54%) fulfilled our criteria for likely CAP. Median duration of treatment was 10 days. Of empirical treatments, 36 (57%) only involved penicillin. None of the children had neutropenia or complications, and only two needed intensive care.
CONCLUSION: Only half of children receiving antibiotics for suspected CAP were likely to have bacterial infection. Despite no obvious reason, antibiotic treatment was longer than currently recommended.
© 2021 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica.

Entities:  

Keywords:  antibiotics; c-reactive protein; community-acquired pneumonia; paediatric pneumonia; radiologically confirmed pneumonia

Year:  2021        PMID: 33576065     DOI: 10.1111/apa.15808

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN: 0803-5253            Impact factor:   2.299


  1 in total

1.  Shift in Clinical Profile of Hospitalized Pneumonia in Children in the Non-pharmaceutical Interventions Period During the COVID-19 Pandemic: A Prospective Multicenter Study.

Authors:  Alexis Rybak; Naïm Ouldali; François Angoulvant; Philippe Minodier; Sandra Biscardi; Fouad Madhi; Isabelle Hau; Audrey Santos; Emilie Bouvy; François Dubos; Alain Martinot; Marie-Aliette Dommergues; Christèle Gras-Le Guen; Elise Launay; Karine Levieux; Ferielle Zenkhri; Irina Craiu; Mathie Lorrot; Yves Gillet; Ellia Mezgueldi; Albert Faye; Stéphane Béchet; Emmanuelle Varon; Robert Cohen; Corinne Levy
Journal:  Front Pediatr       Date:  2022-03-22       Impact factor: 3.418

  1 in total

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