Literature DB >> 33575860

Who is managing menopausal symptoms, sexual problems, mood and sleep disturbance after breast cancer and is it working? Findings from a large community-based survey of breast cancer survivors.

Michelle Peate1, Christobel Saunders2, Paul Cohen3, Martha Hickey4.   

Abstract

PURPOSE: To determine the nature and severity of vasomotor symptoms, sexual problems, mood and sleep disturbance in community-dwelling breast cancer patients, whether and where they received treatment for these symptoms and their satisfaction with treatment received.
METHODS: Online cross-sectional survey distributed through Breast Cancer Network Australia (BCNA).
RESULTS: 524/2286 women responded to the invitation to participate. Of these, 74% (385/523) reported symptoms of interest and were included in the analysis. Mean age was 55.2 years and mean time since breast cancer diagnosis was 5.7 years. Most (66%) had received chemotherapy and were taking endocrine therapy (64%). The most common symptoms were hot flushes/night sweats and sleep disturbance (both 89%), vaginal dryness (75%), mood swings (62%) and sexual problems (60%). Symptoms were mild (21-33%) or moderate (21-38%) in around one third and severe in up to one quarter (8-26%). Symptoms affected the ability to "get on with their life" for 36%, predicted by severity of hot flushes (OR 1.4), sleep disturbance (OR 1.3), mood disturbance (OR 1.3), and sexual problems (OR 1.3). Only 32% were offered treatment, mostly delivered by GPs (33%) or oncologists (26%). Only 49% found this "somewhat effective" and 34% found it ineffective. The majority (60%) wanted more support to manage their symptoms.
CONCLUSION: Menopausal symptoms, sexual problems, mood and sleep difficulties are common after breast cancer and often not effectively managed. There is an unmet need for coordinated care providing effective treatments.

Entities:  

Keywords:  Breast cancer; Menopause; Satisfaction with care; Symptom management; Unmet needs

Year:  2021        PMID: 33575860     DOI: 10.1007/s10549-021-06117-7

Source DB:  PubMed          Journal:  Breast Cancer Res Treat        ISSN: 0167-6806            Impact factor:   4.872


  37 in total

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2.  Menopausal symptoms in breast cancer survivors nearly 6 years after diagnosis.

Authors:  Susan R Davis; Mary Panjari; Penelope J Robinson; Pamela Fradkin; Robin J Bell
Journal:  Menopause       Date:  2014-10       Impact factor: 2.953

3.  Menopausal symptoms in breast cancer survivors.

Authors:  J S Carpenter; M A Andrykowski
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4.  Nature and severity of menopausal symptoms and their impact on quality of life and sexual function in cancer survivors compared with women without a cancer history.

Authors:  Jennifer L Marino; Christobel M Saunders; Laura I Emery; Helena Green; Dorota A Doherty; Martha Hickey
Journal:  Menopause       Date:  2014-03       Impact factor: 2.953

5.  Menopause after breast cancer: a survey on breast cancer survivors.

Authors:  Nicoletta Biglia; Marilena Cozzarella; Franca Cacciari; Riccardo Ponzone; Riccardo Roagna; Furio Maggiorotto; Piero Sismondi
Journal:  Maturitas       Date:  2003-05-30       Impact factor: 4.342

6.  HABITS (hormonal replacement therapy after breast cancer--is it safe?), a randomised comparison: trial stopped.

Authors:  L Holmberg; H Anderson
Journal:  Lancet       Date:  2004-02-07       Impact factor: 79.321

Review 7.  Late and long-term effects of breast cancer treatment and surveillance management for the general practitioner.

Authors:  Megan Kenyon; Deborah K Mayer; Anna Kate Owens
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8.  Safety and efficacy of tibolone in breast-cancer patients with vasomotor symptoms: a double-blind, randomised, non-inferiority trial.

Authors:  Peter Kenemans; Nigel J Bundred; Jean-Michel Foidart; Ernst Kubista; Bo von Schoultz; Piero Sismondi; Rena Vassilopoulou-Sellin; Cheng Har Yip; Jan Egberts; Mirjam Mol-Arts; Roel Mulder; Steve van Os; Matthias W Beckmann
Journal:  Lancet Oncol       Date:  2009-01-23       Impact factor: 41.316

9.  Participant-Reported Symptoms and Their Effect on Long-Term Adherence in the International Breast Cancer Intervention Study I (IBIS I).

Authors:  Samuel George Smith; Ivana Sestak; Anthony Howell; John Forbes; Jack Cuzick
Journal:  J Clin Oncol       Date:  2017-06-29       Impact factor: 44.544

10.  Pain and Menopause Symptoms of Breast Cancer Patients with Adjuvant Hormonal Therapy in Korea: Secondary Analysis.

Authors:  Myungsun Yi; Eunkyung Hwang
Journal:  Asia Pac J Oncol Nurs       Date:  2018 Jul-Sep
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  5 in total

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4.  Supporting adjuvant endocrine therapy adherence in women with breast cancer: the development of a complex behavioural intervention using Intervention Mapping guided by the Multiphase Optimisation Strategy.

Authors:  Sophie M C Green; David P French; Christopher D Graham; Louise H Hall; Nikki Rousseau; Robbie Foy; Jane Clark; Catherine Parbutt; Erin Raine; Benjamin Gardner; Galina Velikova; Sally J L Moore; Jacqueline Buxton; Samuel G Smith
Journal:  BMC Health Serv Res       Date:  2022-08-24       Impact factor: 2.908

5.  Sleep medication use and risk of fractures in breast cancer survivors.

Authors:  Reina Haque; Rowan T Chlebowski; LieHong Chen
Journal:  Breast Cancer Res Treat       Date:  2021-09-29       Impact factor: 4.872

  5 in total

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