| Literature DB >> 33573641 |
Kenji Gonda1,2, Koichi Suzuki3,4, Yumi Sunabe4, Koji Kono4, Seiichi Takenoshita4.
Abstract
Human T-cell leukemia virus type 1 was isolated as the retrovirus to be identified in humans. Here, we focused on Ficus pumila L. as a factor that be effective against human T-cell leukemia virus type 1. The significant and novel findings is that symptoms of patients with drinking Ficus pumila L. extracts did not worsen despite a lack of aggressive pharmacotherapy against adult T-cell leukemia, a human T-cell leukemia virus type 1-associated myelopathy, or T-cell leukemia virus type 1 uveitis. Twenty-eight of the 194 inpatients who underwent showed high levels of human T-cell leukemia virus type 1.Among human T-cell leukemia virus type 1-infected patients, those who were administered Ficus pumila L. extracts had no human T-cell leukemia virus type 1-related symptoms, while those who were not administered Ficus pumila L. extracts had human T-cell leukemia virus type 1-related diseases and a significantly poorer prognosis. This suggests that the Ficus pumila L. extracts may show some utility against virus infection.Entities:
Keywords: Ficus pumila L.; HTLV-1; Ooitabi; miRNA
Year: 2021 PMID: 33573641 PMCID: PMC7877332 DOI: 10.1186/s12937-021-00672-x
Source DB: PubMed Journal: Nutr J ISSN: 1475-2891 Impact factor: 3.271