Literature DB >> 33573641

Ficus pumila L. improves the prognosis of patients infected with HTLV-1, an RNA virus.

Kenji Gonda1,2, Koichi Suzuki3,4, Yumi Sunabe4, Koji Kono4, Seiichi Takenoshita4.   

Abstract

Human T-cell leukemia virus type 1 was isolated as the retrovirus to be identified in humans. Here, we focused on Ficus pumila L. as a factor that be effective against human T-cell leukemia virus type 1. The significant and novel findings is that symptoms of patients with drinking Ficus pumila L. extracts did not worsen despite a lack of aggressive pharmacotherapy against adult T-cell leukemia, a human T-cell leukemia virus type 1-associated myelopathy, or T-cell leukemia virus type 1 uveitis. Twenty-eight of the 194 inpatients who underwent showed high levels of human T-cell leukemia virus type 1.Among human T-cell leukemia virus type 1-infected patients, those who were administered Ficus pumila L. extracts had no human T-cell leukemia virus type 1-related symptoms, while those who were not administered Ficus pumila L. extracts had human T-cell leukemia virus type 1-related diseases and a significantly poorer prognosis. This suggests that the Ficus pumila L. extracts may show some utility against virus infection.

Entities:  

Keywords:  Ficus pumila L.; HTLV-1; Ooitabi; miRNA

Year:  2021        PMID: 33573641      PMCID: PMC7877332          DOI: 10.1186/s12937-021-00672-x

Source DB:  PubMed          Journal:  Nutr J        ISSN: 1475-2891            Impact factor:   3.271


  10 in total

1.  Dietary apigenin reduces LPS-induced expression of miR-155 restoring immune balance during inflammation.

Authors:  Daniel Arango; Mayra Diosa-Toro; Laura S Rojas-Hernandez; Jessica L Cooperstone; Steven J Schwartz; Xiaokui Mo; Jinmai Jiang; Thomas D Schmittgen; Andrea I Doseff
Journal:  Mol Nutr Food Res       Date:  2015-02-23       Impact factor: 5.914

2.  Polycomb-mediated loss of miR-31 activates NIK-dependent NF-κB pathway in adult T cell leukemia and other cancers.

Authors:  Makoto Yamagishi; Kazumi Nakano; Ariko Miyake; Tadanori Yamochi; Yayoi Kagami; Akihisa Tsutsumi; Yuka Matsuda; Aiko Sato-Otsubo; Satsuki Muto; Atae Utsunomiya; Kazunari Yamaguchi; Kaoru Uchimaru; Seishi Ogawa; Toshiki Watanabe
Journal:  Cancer Cell       Date:  2012-01-17       Impact factor: 31.743

3.  Inhibition of miR31 and miR92a as Oncological Biomarkers in RKO Colon Cancer Cells Treated with Kaempferol-3-O-Glycoside Isolated from Black Bean.

Authors:  Janet Alejandra Gutierrez-Uribe; Mauricio Salinas-Santander; Delia Serna-Guerrero; Sergio Roman Othon Serna-Saldivar; Ana Maria Rivas-Estilla; Clara Patricia Rios-Ibarra
Journal:  J Med Food       Date:  2019-08-23       Impact factor: 2.786

4.  Kaempferol protects chondrogenic ATDC5 cells against inflammatory injury triggered by lipopolysaccharide through down-regulating miR-146a.

Authors:  Rui Jiang; Peng Hao; Guisheng Yu; Chuanan Liu; Chuandong Yu; Yan Huang; Yongkun Wang
Journal:  Int Immunopharmacol       Date:  2019-02-15       Impact factor: 4.932

5.  MicroRNA miR-146a is induced by HTLV-1 tax and increases the growth of HTLV-1-infected T-cells.

Authors:  Mariko Tomita; Yuetsu Tanaka; Naoki Mori
Journal:  Int J Cancer       Date:  2009-12-16       Impact factor: 7.396

6.  Analgesic and Anti-Inflammatory Activities of Methanol Extract of Ficus pumila L. in Mice.

Authors:  Chi-Ren Liao; Chun-Pin Kao; Wen-Huang Peng; Yuan-Shiun Chang; Shang-Chih Lai; Yu-Ling Ho
Journal:  Evid Based Complement Alternat Med       Date:  2012-05-14       Impact factor: 2.629

7.  Modulation of hippocampal gene expression of microRNA-146a/microRNA-155-nuclear factor-kappa B inflammatory signaling by troxerutin in healthy and diabetic rats.

Authors:  Raana Yavari; Reza Badalzadeh; Mohammad Reza Alipour; Seyed Mahmoud Tabatabaei
Journal:  Indian J Pharmacol       Date:  2016 Nov-Dec       Impact factor: 1.200

8.  Important Roles of Cellular MicroRNA miR-155 in Leukemogenesis by Human T-Cell Leukemia Virus Type 1 Infection.

Authors:  Mariko Tomita
Journal:  ISRN Microbiol       Date:  2012-09-18

9.  Complex role of microRNAs in HTLV-1 infections.

Authors:  Gavin C Sampey; Rachel Van Duyne; Robert Currer; Ravi Das; Aarthi Narayanan; Fatah Kashanchi
Journal:  Front Genet       Date:  2012-12-17       Impact factor: 4.599

10.  Potential curing and beneficial effects of Ooitabi (Ficus pumila L.) on hypertension and dyslipidaemia in Okinawa.

Authors:  K Suzuki; K Gonda; Y Kishimoto; Y Katsumoto; S Takenoshita
Journal:  J Hum Nutr Diet       Date:  2020-08-26       Impact factor: 3.089

  10 in total
  1 in total

1.  Ingestion of Okinawa Island Vegetables Increases IgA Levels and Prevents the Spread of Influenza RNA Viruses.

Authors:  Kenji Gonda; Hideto Kanazawa; Goki Maeda; Chisa Matayoshi; Naoto Hirose; Yukiteru Katsumoto; Koji Kono; Seiichi Takenoshita
Journal:  Nutrients       Date:  2021-05-22       Impact factor: 5.717

  1 in total

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