Literature DB >> 33573132

miRNAs and Biomarkers in Testicular Germ Cell Tumors: An Update.

Marco De Martino1,2, Paolo Chieffi3, Francesco Esposito1.   

Abstract

Testicular germ cell tumors (TGCTs) are the leading form of solid cancer and death affecting males between the ages of 20 and 40. Today, their surgical resection and chemotherapy are the treatments of first choice, even if sometimes this is not enough to save the lives of patients with TGCT. As seen for several tumors, the deregulation of microRNAs (miRNAs) is also a key feature in TGCTs. miRNAs are small molecules of RNA with biological activity that are released into biological fluids by testicular cancer cells. Their presence, therefore, can be detected and monitored by considering miRNAs as diagnostic and prognostic markers for TGCTs. The purpose of this review is to collect all the studies executed on miRNAs that have a potential role as biomarkers for testicular tumors.

Entities:  

Keywords:  biomarker; microRNA; testicular germ cell tumors

Year:  2021        PMID： 33573132      PMCID： PMC7866514          DOI： 10.3390/ijms22031380

Source DB:  PubMed          Journal:  Int J Mol Sci        ISSN： 1422-0067            Impact factor:   5.923


  97 in total

1.  MicroRNA-223 functions as an oncogene in human gastric cancer by targeting FBXW7/hCdc4.

Authors:  Jinhai Li; Yuanyuan Guo; Xiaodi Liang; Ming Sun; Guoliang Wang; Wei De; Wenxi Wu
Journal:  J Cancer Res Clin Oncol       Date:  2012-01-22       Impact factor: 4.553

2.  The high-mobility group A1-estrogen receptor β nuclear interaction is impaired in human testicular seminomas.

Authors:  Francesco Esposito; Francesca Boscia; Vincenzo Gigantino; Mara Tornincasa; Alfredo Fusco; Renato Franco; Paolo Chieffi
Journal:  J Cell Physiol       Date:  2012-12       Impact factor: 6.384

3.  A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors.

Authors:  P Mathijs Voorhoeve; Carlos le Sage; Mariette Schrier; Ad J M Gillis; Hans Stoop; Remco Nagel; Ying-Poi Liu; Josyanne van Duijse; Jarno Drost; Alexander Griekspoor; Eitan Zlotorynski; Norikazu Yabuta; Gabriella De Vita; Hiroshi Nojima; Leendert H J Looijenga; Reuven Agami
Journal:  Cell       Date:  2006-03-24       Impact factor: 41.582

Review 4.  MicroRNA and cancer.

Authors:  Martin D Jansson; Anders H Lund
Journal:  Mol Oncol       Date:  2012-10-09       Impact factor: 6.603

5.  PATZ1 gene has a critical role in the spermatogenesis and testicular tumours.

Authors:  M Fedele; R Franco; G Salvatore; M P Paronetto; F Barbagallo; R Pero; L Chiariotti; C Sette; D Tramontano; G Chieffi; A Fusco; P Chieffi
Journal:  J Pathol       Date:  2008-05       Impact factor: 7.996

6.  MiR-371a-3p Serum Levels Are Increased in Recurrence of Testicular Germ Cell Tumor Patients.

Authors:  Angelika Terbuch; Jan B Adiprasito; Verena Stiegelbauer; Maximilian Seles; Christiane Klec; Georg P Pichler; Margit Resel; Florian Posch; Anna L Lembeck; Herbert Stöger; Joanna Szkandera; Karl Pummer; Thomas Bauernhofer; Georg C Hutterer; Armin Gerger; Michael Stotz; Martin Pichler
Journal:  Int J Mol Sci       Date:  2018-10-12       Impact factor: 5.923

Review 7.  Current Concepts of Non-Coding RNAs in the Pathogenesis of Non-Clear Cell Renal Cell Carcinoma.

Authors:  Dominik A Barth; Ondrej Slaby; Christiane Klec; Jaroslav Juracek; Rares Drula; George A Calin; Martin Pichler
Journal:  Cancers (Basel)       Date:  2019-10-17       Impact factor: 6.639

8.  miR-371a-3p, miR-373-3p and miR-367-3p as Serum Biomarkers in Metastatic Testicular Germ Cell Cancers Before, During and After Chemotherapy.

Authors:  Ximena Rosas Plaza; Ton van Agthoven; Coby Meijer; Marcel A T M van Vugt; Steven de Jong; Jourik A Gietema; Leendert H J Looijenga
Journal:  Cells       Date:  2019-10-08       Impact factor: 6.600

9.  17-beta-estradiol elicits genomic and non-genomic responses in mouse male germ cells.

Authors:  Elena Vicini; Maria Loiarro; Silvia Di Agostino; Serena Corallini; Federica Capolunghi; Rita Carsetti; Paolo Chieffi; Raffaele Geremia; Mario Stefanini; Claudio Sette
Journal:  J Cell Physiol       Date:  2006-01       Impact factor: 6.384

10.  Risk stratification for febrile neutropenia in patients with testicular germ cell tumors.

Authors:  Angelika Terbuch; Florian Posch; Richard Partl; Brigitte Zurl; Thomas Bauernhofer; Martin Pichler; Joanna Szkandera; Georg C Hutterer; Karl Pummer; Karin S Kapp; Herbert Stöger; Armin Gerger; Michael Stotz
Journal:  Cancer Med       Date:  2018-01-19       Impact factor: 4.452
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  4 in total

1.  Evaluating the Cisplatin Dose Dependence of Testicular Dysfunction Using Creatine Chemical Exchange Saturation Transfer Imaging.

Authors:  Reika Sawaya; Sohei Kuribayashi; Junpei Ueda; Shigeyoshi Saito
Journal:  Diagnostics (Basel)       Date:  2022-04-21

2.  Long Non-Coding RNA RFPL3S Functions as a Biomarker of Prognostic and Immunotherapeutic Prediction in Testicular Germ Cell Tumor.

Authors:  Jie Guo; Shuang Wang; Zhenzhen Jiang; Le Tang; Zhizhong Liu; Jian Cao; Zhaolan Hu; Xiao Chen; Yanwei Luo; Hao Bo
Journal:  Front Immunol       Date:  2022-05-20       Impact factor: 8.786

Review 3.  Testicular Germ Cell Tumours and Proprotein Convertases.

Authors:  Aitziber Velado-Eguskiza; Laura Gomez-Santos; Iker Badiola; Francisco José Sáez; Edurne Alonso
Journal:  Cancers (Basel)       Date:  2022-03-23       Impact factor: 6.639

4.  First Evidence of the Expression and Localization of Prothymosin α in Human Testis and Its Involvement in Testicular Cancers.

Authors:  Massimo Venditti; Davide Arcaniolo; Marco De Sio; Sergio Minucci
Journal:  Biomolecules       Date:  2022-08-31
  4 in total

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