Henrik Szőke1,2, Márta Maródi3, Jan Vagedes4,5, Balázs Székely6, István Magyarosi7,8, Adél Bedő9, Veronika Fellegi9, Krisztina Somogyvári10, Péter Móricz7,8. 1. Department of IM, Faculty of Health Sciences, University of Pécs, 7623 Pécs, Hungary. 2. Doctoral School, Faculty of Health Sciences, University of Pécs, 7623 Pécs, Hungary. 3. Department of Otolaryngology, Szt. Borbála Hospital, 2800 Tatabánya, Hungary. 4. Department of Neonatology, University Children's Hospital Tubingen, 72016 Tubingen, Germany. 5. ARCIM Institute (Academic Research in Complementary and Integrative Medicine), 70794 Filderstadt, Germany. 6. Cello Health Insight, Advanced Analytics Manager, London EC1M 7AP, UK. 7. Department of Otolaryngology, Balassa János Hospital, 7100 Szekszárd, Hungary. 8. Doctoral School, Faculty of Medicine, University of Pécs, 7622 Pécs, Hungary. 9. Outpatient Clinic, 8000 Székesfehérvár, Hungary. 10. Department of Otorhinolaryngology and Head-Neck Surgery, Clinical Center, University of Pécs, 7621 Pécs, Hungary.
Abstract
BACKGROUND AND OBJECTIVES: Based on our previous single-center study on optimization of treatment of chronic otitis media with effusion (COME) and adenoid hypertrophy (AH) in children using a noninvasive system approach to lower the necessity of antibiotics, analgesic use, and surgical interventions, we proceeded to perform a multicenter investigation in an outpatient setting. The purpose of the previous prospective study in 2013-2015 was to compare outcomes in the treatment of COME and AH using the noninvasive multimodal integrative method (IM) versus conventional treatment practice (COM). MATERIALS AND METHODS: In this paper, we retrospectively analyze the data of patients treated with the integrative method between 2017 and 2020 in a multicenter setting and compared the outcomes with data from 2013-2015 in order to evaluate generalizability. In both periods, all eligible and willing participants were included and treated with the IM protocol under real-life conditions. The treatment involved pneumatization exercises, education, an antiallergic diet, nasal hygiene, useful constitutional therapy, and thermal interventions (P.E.A.N.U.T.). A total of 48 versus 28 patients, aged 1-8, were assessed, presenting with COME and AH, with moderate to severe hearing impairment at entry. RESULTS: The significant improvement found in both audiometric measures (intact hearing) and tympanometric measures (normal A-type curve) was similar in both datasets with respect to conventional treatment. The new data confirms that the P.E.A.N.U.T. method results in a significant reduction of antibiotics, analgesic use, and surgical interventions. CONCLUSION: In this multicenter trial, we confirm the effectiveness of the noninvasive system approach for the treatment of COME in lowering the need for antibiotics and analgesic use and elective surgery. This could be especially important with respect to a generally observed increase in antibiotic resistance. The method is easy to perform in different clinical settings and is effective, safe, and well-tolerated.
BACKGROUND AND OBJECTIVES: Based on our previous single-center study on optimization of treatment of chronic otitis media with effusion (COME) and adenoid hypertrophy (AH) in children using a noninvasive system approach to lower the necessity of antibiotics, analgesic use, and surgical interventions, we proceeded to perform a multicenter investigation in an outpatient setting. The purpose of the previous prospective study in 2013-2015 was to compare outcomes in the treatment of COME and AH using the noninvasive multimodal integrative method (IM) versus conventional treatment practice (COM). MATERIALS AND METHODS: In this paper, we retrospectively analyze the data of patients treated with the integrative method between 2017 and 2020 in a multicenter setting and compared the outcomes with data from 2013-2015 in order to evaluate generalizability. In both periods, all eligible and willing participants were included and treated with the IM protocol under real-life conditions. The treatment involved pneumatization exercises, education, an antiallergic diet, nasal hygiene, useful constitutional therapy, and thermal interventions (P.E.A.N.U.T.). A total of 48 versus 28 patients, aged 1-8, were assessed, presenting with COME and AH, with moderate to severe hearing impairment at entry. RESULTS: The significant improvement found in both audiometric measures (intact hearing) and tympanometric measures (normal A-type curve) was similar in both datasets with respect to conventional treatment. The new data confirms that the P.E.A.N.U.T. method results in a significant reduction of antibiotics, analgesic use, and surgical interventions. CONCLUSION: In this multicenter trial, we confirm the effectiveness of the noninvasive system approach for the treatment of COME in lowering the need for antibiotics and analgesic use and elective surgery. This could be especially important with respect to a generally observed increase in antibiotic resistance. The method is easy to perform in different clinical settings and is effective, safe, and well-tolerated.
Entities:
Keywords:
adenoid hypertrophy; analgesics; antibiotics; children; chronic otitis media with effusion; integrative therapy; surgical interventions
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