Literature DB >> 33572889

Human Lectins, Their Carbohydrate Affinities and Where to Find Them.

Cláudia D Raposo1, André B Canelas2, M Teresa Barros1.   

Abstract

Lectins are a class of proteins responsible for several biological roles such as cell-cell interactions, signaling pathways, and several innate immune responses against pathogens. Since lectins are able to bind to carbohydrates, they can be a viable target for targeted drug delivery systems. In fact, several lectins were approved by Food and Drug Administration for that purpose. Information about specific carbohydrate recognition by lectin receptors was gathered herein, plus the specific organs where those lectins can be found within the human body.

Entities:  

Keywords:  biological applications; carbohydrate specific recognition; human lectins; protein expression; targeted drug delivery systems

Mesh:

Substances:

Year:  2021        PMID: 33572889      PMCID: PMC7911577          DOI: 10.3390/biom11020188

Source DB:  PubMed          Journal:  Biomolecules        ISSN: 2218-273X


  157 in total

Review 1.  Immunoregulatory functions of surfactant proteins.

Authors:  Jo Rae Wright
Journal:  Nat Rev Immunol       Date:  2005-01       Impact factor: 53.106

2.  Ligand interactions of the cation-dependent mannose 6-phosphate receptor. Comparison with the cation-independent mannose 6-phosphate receptor.

Authors:  P Y Tong; S Kornfeld
Journal:  J Biol Chem       Date:  1989-05-15       Impact factor: 5.157

3.  Eosinophil-granule major basic protein, a C-type lectin, binds heparin.

Authors:  G Jawahar Swaminathan; David G Myszka; Phinikoula S Katsamba; Lyo E Ohnuki; Gerald J Gleich; K Ravi Acharya
Journal:  Biochemistry       Date:  2005-11-01       Impact factor: 3.162

4.  Crystal structure of the carbohydrate recognition domain of the H1 subunit of the asialoglycoprotein receptor.

Authors:  M Meier; M D Bider; V N Malashkevich; M Spiess; P Burkhard
Journal:  J Mol Biol       Date:  2000-07-21       Impact factor: 5.469

5.  Molecular cloning and characterization of human chondrolectin, a novel type I transmembrane protein homologous to C-type lectins.

Authors:  Lin Weng; Patrick Smits; Jan Wauters; Jozef Merregaert
Journal:  Genomics       Date:  2002-07       Impact factor: 5.736

6.  Structural basis of sugar-recognizing ubiquitin ligase.

Authors:  Tsunehiro Mizushima; Takeshi Hirao; Yukiko Yoshida; Soo Jae Lee; Tomoki Chiba; Kazuhiro Iwai; Yoshiki Yamaguchi; Koichi Kato; Tomitake Tsukihara; Keiji Tanaka
Journal:  Nat Struct Mol Biol       Date:  2004-02-29       Impact factor: 15.369

7.  Characterization of sugar binding by the mannose receptor family member, Endo180.

Authors:  Lucy East; Sally Rushton; Maureen E Taylor; Clare M Isacke
Journal:  J Biol Chem       Date:  2002-10-23       Impact factor: 5.157

Review 8.  Siglecs as positive and negative regulators of the immune system.

Authors:  Paul R Crocker; Pierre Redelinghuys
Journal:  Biochem Soc Trans       Date:  2008-12       Impact factor: 5.407

9.  The fourth immunoglobulin-like domain of NCAM contains a carbohydrate recognition domain for oligomannosidic glycans implicated in association with L1 and neurite outgrowth.

Authors:  R Horstkorte; M Schachner; J P Magyar; T Vorherr; B Schmitz
Journal:  J Cell Biol       Date:  1993-06       Impact factor: 10.539

10.  Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation.

Authors:  Shaun Spence; Michelle K Greene; François Fay; Emily Hams; Sean P Saunders; Umar Hamid; Marianne Fitzgerald; Jonathan Beck; Baljinder K Bains; Peter Smyth; Efrosyni Themistou; Donna M Small; Daniela Schmid; Cecilia M O'Kane; Denise C Fitzgerald; Sharif M Abdelghany; James A Johnston; Padraic G Fallon; James F Burrows; Daniel F McAuley; Adrien Kissenpfennig; Christopher J Scott
Journal:  Sci Transl Med       Date:  2015-09-02       Impact factor: 17.956

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  5 in total

1.  KIT Mutations Correlate with Higher Galectin Levels and Brain Metastasis in Breast and Non-Small Cell Lung Cancer.

Authors:  Avery T Funkhouser; Alexander M Strigenz; Bailey B Blair; Andrew P Miller; Jonah C Shealy; Joseph A Ewing; Julie C Martin; Christopher R Funk; William J Edenfield; Anna V Blenda
Journal:  Cancers (Basel)       Date:  2022-06-03       Impact factor: 6.575

2.  α2,6-Sialylation is Upregulated in Severe COVID-19 Implicating the Complement Cascade.

Authors:  Rui Qin; Emma Kurz; Shuhui Chen; Briana Zeck; Luis Chiribogas; Dana Jackson; Alex Herchen; Tyson Attia; Michael Carlock; Amy Rapkiewicz; Dafna Bar-Sagi; Bruce Ritchie; Ted M Ross; Lara K Mahal
Journal:  medRxiv       Date:  2022-06-08

Review 3.  Glycan-Lectin Interactions as Novel Immunosuppression Drivers in Glioblastoma.

Authors:  Angelica Pace; Fabio Scirocchi; Chiara Napoletano; Ilaria Grazia Zizzari; Luca D'Angelo; Antonio Santoro; Marianna Nuti; Hassan Rahimi; Aurelia Rughetti
Journal:  Int J Mol Sci       Date:  2022-06-05       Impact factor: 6.208

4.  An Evaluation of the Mechanisms of Galacto-Oligosaccharide (GOS)-Induced IgE Cross-Linking on Basophils in GOS Allergy.

Authors:  Li Yuan Gabriella Nadine Lee; Si Yuan Leow; Hongmei Wen; Jian Yi Soh; Wen Chin Chiang; Youjia Zhong; Elizabeth Huiwen Tham; Wenyin Loh; Dianne J Delsing; Bee Wah Lee; Chiung-Hui Huang
Journal:  Front Allergy       Date:  2022-02-28

Review 5.  Seminal Plasma Glycoproteins as Potential Ligands of Lectins Engaged in Immunity Regulation.

Authors:  Beata Olejnik; Mirosława Ferens-Sieczkowska
Journal:  Int J Environ Res Public Health       Date:  2022-08-23       Impact factor: 4.614

  5 in total

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