Literature DB >> 33572120

Bland Embolization of Benign Liver Tumors: Review of the Literature and a Single Center Experience.

Daniel Crawford1, Sailen Naidu2, Indravadan Patel2, Grace Knuttinen2, Sadeer Alzubaidi2, Rahmi Oklu2.   

Abstract

Transarterial embolization has shown promise as a safe, effective, and less invasive treatment modality for benign liver lesions (hemangioma, focal nodular hyperplasia (FNH), and hepatic adenoma (HA)) with fewer complications compared to surgical intervention. There is no consensus regarding the most appropriate embolization material(s) for the treatment of benign liver tumors. The purpose of this study was to review the current literature regarding the transarterial embolization of benign liver tumors and to share our single center experience. This was a non-blinded, retrospective, single-institution review of the bland embolization of benign liver tumors. Clinical data and imaging before and after embolization were used to evaluate lesion response to transarterial embolization. Twelve patients were included in the study. Five patients with six hemangiomas were treated. Pain was a presenting complaint in all five of these patients. The median change in tumor volume was -12.4% and ranged from -30.1% to +42.3%. One patient with two FNH lesions was treated, and both lesion volumes decreased by more than 50%. Six patients with 10 adenomas were treated. Pain was a presenting complaint in three patients, and five patients had a lesion >5 cm. The median change in tumor volume was -67.0% and ranged from -92.9% to +65.8%. Bland transarterial embolization of liver hemangiomas, FNH, and HA can be an effective and minimally invasive treatment modality to control the size and/or symptoms of these lesions. There is a variable response depending on tumor type and the embolization materials used.

Entities:  

Keywords:  adenoma; embolization; focal nodular hyperplasia; hemangioma; liver; neoplasms; vascular and interventional radiology

Year:  2021        PMID: 33572120      PMCID: PMC7915444          DOI: 10.3390/jcm10040658

Source DB:  PubMed          Journal:  J Clin Med        ISSN: 2077-0383            Impact factor:   4.241


  23 in total

1.  Liver abscess complicating embolization of focal nodular hyperplasia.

Authors:  I Pueyo; A Guzmán; F Fernández; M García-Morán; M F Medina; I Faedo; L Rodrigo; J R Jiménez
Journal:  AJR Am J Roentgenol       Date:  1979-10       Impact factor: 3.959

2.  New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada.

Authors:  P Therasse; S G Arbuck; E A Eisenhauer; J Wanders; R S Kaplan; L Rubinstein; J Verweij; M Van Glabbeke; A T van Oosterom; M C Christian; S G Gwyther
Journal:  J Natl Cancer Inst       Date:  2000-02-02       Impact factor: 13.506

3.  Bland embolization in the treatment of hepatic adenomas: preliminary experience.

Authors:  Ajita Deodhar; Lynn A Brody; Anne M Covey; Karen T Brown; George I Getrajdman
Journal:  J Vasc Interv Radiol       Date:  2011-06       Impact factor: 3.464

4.  Safety and efficacy of radiofrequency ablation for hepatocellular adenoma.

Authors:  Mark G van Vledder; Sanne M van Aalten; Turkan Terkivatan; Robert A de Man; Trude Leertouwer; Jan N M Ijzermans
Journal:  J Vasc Interv Radiol       Date:  2011-06       Impact factor: 3.464

Review 5.  Uncommon evolutions and complications of common benign liver lesions.

Authors:  Federica Vernuccio; Maxime Ronot; Marco Dioguardi Burgio; Jérôme Lebigot; Wassim Allaham; Christophe Aubé; Giuseppe Brancatelli; Valérie Vilgrain
Journal:  Abdom Radiol (NY)       Date:  2018-08

6.  Transarterial Bleomycin-Lipiodol Embolization (B/LE) for Symptomatic Giant Hepatic Hemangioma.

Authors:  Shahram Akhlaghpoor; Pooya Torkian; Jafar Golzarian
Journal:  Cardiovasc Intervent Radiol       Date:  2018-06-19       Impact factor: 2.740

Review 7.  Management of Hepatocellular Adenoma: Recent Advances.

Authors:  Shefali Agrawal; Sheela Agarwal; Thomas Arnason; Sanjay Saini; Jacques Belghiti
Journal:  Clin Gastroenterol Hepatol       Date:  2014-06-05       Impact factor: 11.382

8.  Evaluation of 300 minimally invasive liver resections at a single institution: less is more.

Authors:  Alan J Koffron; Greg Auffenberg; Robert Kung; Michael Abecassis
Journal:  Ann Surg       Date:  2007-09       Impact factor: 12.969

9.  Management of hepatocellular adenoma: comparison of resection, embolization and observation.

Authors:  Ami M Karkar; Laura H Tang; Nilesh D Kashikar; Mithat Gonen; Stephen B Solomon; Ronald P Dematteo; Michael I D' Angelica; Camilo Correa-Gallego; William R Jarnagin; Yuman Fong; George I Getrajdman; Peter Allen; T Peter Kingham
Journal:  HPB (Oxford)       Date:  2012-10-09       Impact factor: 3.647

10.  Adequate symptom relief justifies hepatic resection for benign disease.

Authors:  Bram Fioole; Marike Kokke; Richard van Hillegersberg; Inne H Borel Rinkes
Journal:  BMC Surg       Date:  2005-04-01       Impact factor: 2.102

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