Nicola Luigi Bragazzi1,2,3, Wen Zhong1, Jingxian Shu4, Arsalan Abu Much5,6, Dor Lotan5,6, Avishay Grupper5,6, Arwa Younis7, Haijiang Dai2. 1. Department of General Medicine, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, Hunan 410008, China. 2. Centre for Disease Modelling, York University, 4700 Keele St, Toronto, ON M3J 1P3, Canada. 3. Department of Health Sciences (DISSAL), Postgraduate School of Public Health, University of Genoa, Via Balbi 5, Genova 16126, Italy. 4. Department of Pharmacy, The Fifth Affiliated Hospital, Sun Yat-sen University, 52 Mei Hua East Road, Zhuhai, Guangdong 519000, China. 5. Leviev Heart Center, Sheba Medical Center, Tel HaShomer, Israel. 6. Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel. 7. Clinical Cardiovascular Research Center, University of Rochester Medical Center, 265 Crittenden Boulevard, Rochester, NY 14620, USA.
Abstract
AIMS: To provide the first systematic analysis of the burden and underlying causes of heart failure (HF) in 195 countries and territories from 1990 to 2017. METHODS AND RESULTS: We collected detailed information on prevalence, years lived with disability (YLDs), and underlying causes of HF from the Global Burden of Disease study 2017. Numbers and age-standardized rates of HF prevalence and YLDs were compared by age, sex, socio-demographic index (SDI), and location. The proportions of HF age-standardized prevalence rates due to 23 underlying causes were also presented. Globally, the age-standardized prevalence and YLD rates of HF in 2017 were 831.0 and 128.2 per 100 000 people, a decrease of -7.2% and -0.9% from 1990, respectively. Nevertheless, the absolute numbers of HF prevalent cases and YLDs have increased by 91.9% and 106.0% from 1990, respectively. There is significant geographic and socio-demographic variation in the levels and trends of HF burden from 1990 to 2017. Among all causes of HF, ischaemic heart disease accounted for the highest proportion (26.5%) of age-standardized prevalence rate of HF in 2017, followed by hypertensive heart disease (26.2%), chronic obstructive pulmonary disease (23.4%). CONCLUSION: HF remains a serious public health problem worldwide, with increasing age-standardized prevalence and YLD rates in countries with relatively low SDI. More geo-specific strategies aimed at preventing underlying causes and improving medical care for HF are warranted to reduce the future burden of this condition.
AIMS: To provide the first systematic analysis of the burden and underlying causes of heart failure (HF) in 195 countries and territories from 1990 to 2017. METHODS AND RESULTS: We collected detailed information on prevalence, years lived with disability (YLDs), and underlying causes of HF from the Global Burden of Disease study 2017. Numbers and age-standardized rates of HF prevalence and YLDs were compared by age, sex, socio-demographic index (SDI), and location. The proportions of HF age-standardized prevalence rates due to 23 underlying causes were also presented. Globally, the age-standardized prevalence and YLD rates of HF in 2017 were 831.0 and 128.2 per 100 000 people, a decrease of -7.2% and -0.9% from 1990, respectively. Nevertheless, the absolute numbers of HF prevalent cases and YLDs have increased by 91.9% and 106.0% from 1990, respectively. There is significant geographic and socio-demographic variation in the levels and trends of HF burden from 1990 to 2017. Among all causes of HF, ischaemic heart disease accounted for the highest proportion (26.5%) of age-standardized prevalence rate of HF in 2017, followed by hypertensive heart disease (26.2%), chronic obstructive pulmonary disease (23.4%). CONCLUSION: HF remains a serious public health problem worldwide, with increasing age-standardized prevalence and YLD rates in countries with relatively low SDI. More geo-specific strategies aimed at preventing underlying causes and improving medical care for HF are warranted to reduce the future burden of this condition.
Authors: Gabriele G Schiattarella; Pilar Alcaide; Gianluigi Condorelli; Thomas G Gillette; Stephane Heymans; Elizabeth A V Jones; Marinos Kallikourdis; Andrew Lichtman; Federica Marelli-Berg; Sanjiv Shah; Edward B Thorp; Joseph A Hill Journal: Nat Cardiovasc Res Date: 2022-03-14
Authors: Peter Jackson; Trishul Siddharthan; Ivet T Cordoba Torres; Barth A Green; Chantal Jean-Pierre Policard; Jerry Degraff; Roma Padalkar; Kathryn B Logothetis; Jeffrey A Gold; Alexander C Fort Journal: ATS Sch Date: 2022-02-17