Literature DB >> 33571973

Al2O3:C optically stimulated luminescence dosimeters (OSLDs) for ultra-high dose rate proton dosimetry.

Jeppe Brage Christensen1, Michele Togno2, Konrad Pawel Nesteruk2, Serena Psoroulas2, David Meer2, Damien Charles Weber2,3,4, Tony Lomax2,5, Eduardo G Yukihara1, Sairos Safai2.   

Abstract

The response of Al2O3:C optically stimulated luminescence detectors (OSLDs) was investigated in a 250 MeV pencil proton beam. The OSLD response was mapped for a wide range of average dose rates up to 9000 Gy s-1, corresponding to a ∼150 kGy s-1instantaneous dose rate in each pulse. Two setups for ultra-high dose rate (FLASH) experiments are presented, which enable OSLDs or biological samples to be irradiated in either water-filled vials or cylinders. The OSLDs were found to be dose rate independent for all dose rates, with an average deviation <1% relative to the nominal dose for average dose rates of (1-1000) Gy s-1when irradiated in the two setups. A third setup for irradiations in a 9000 Gy s-1pencil beam is presented, where OSLDs are distributed in a 3 × 4 grid. Calculations of the signal averaging of the beam over the OSLDs were in agreement with the measured response at 9000 Gy s-1. Furthermore, a new method was presented to extract the beam spot size of narrow pencil beams, which is in agreement within a standard deviation with results derived from radiochromic films. The Al2O3:C OSLDs were found applicable to support radiobiological experiments in proton beams at ultra-high dose rates. Creative Commons Attribution license.

Entities:  

Keywords:  Al2O3:C; FLASH; optically stimulated luminescence; proton dosimetry; ultra-high dose rate

Year:  2021        PMID: 33571973     DOI: 10.1088/1361-6560/abe554

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  3 in total

1.  Optically stimulated luminescence in state-of-the-art LYSO:Ce scintillators enables high spatial resolution 3D dose imaging.

Authors:  Mads L Jensen; Rosana M Turtos; Jacob S Nyemann; Ludvig P Muren; Brian Julsgaard; Peter Balling
Journal:  Sci Rep       Date:  2022-05-18       Impact factor: 4.996

2.  Improved simultaneous LET and dose measurements in proton therapy.

Authors:  Jeppe Brage Christensen; Michele Togno; Lily Bossin; Oskari Ville Pakari; Sairos Safai; Eduardo Gardenali Yukihara
Journal:  Sci Rep       Date:  2022-05-18       Impact factor: 4.996

3.  Ultra-high dose rate dosimetry: Challenges and opportunities for FLASH radiation therapy.

Authors:  Francesco Romano; Claude Bailat; Patrik Gonçalves Jorge; Michael Lloyd Franz Lerch; Arash Darafsheh
Journal:  Med Phys       Date:  2022-05-07       Impact factor: 4.506

  3 in total

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