Literature DB >> 33568033

Glycyrrhizin as a Potential Treatment for the Novel Coronavirus (COVID-19).

Habeb Al-Kamel1, Oliver Grundmann1.   

Abstract

COVID-19 is an emerging viral infection of zoonotic origin that is closely related to the severe acute respiratory syndrome coronavirus (SARS-CoV) that caused an outbreak in 2003. Therefore, scientists named the new virus SARS-CoV-2. On March 11, 2020, The World Health Organization (WHO) recognized COVID-19 as a global pandemic. At present, three vaccines have been approved or are being considered for approval by national regulatory agencies to immunize against COVID- 19. However, the vaccines do not remain widely available, and no specific treatment against the virus is available. The pathogenesis and proliferation pathways of SARS-CoV-2 are still not well known. Thus, in this article, the saponin glycyrrhizin is discussed as a new potential therapeutic agent of natural origin (licorice root, Glycyrrhiza glabra) for the potential treatment of COVID-19 infections. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Entities:  

Keywords:  COVID-19; Coronavirus; SARS-COV-2; broad-spectrum antiviral agent; glycyrrhizin; licorice Root.

Mesh:

Substances:

Year:  2021        PMID: 33568033     DOI: 10.2174/1389557521666210210160237

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN: 1389-5575            Impact factor:   3.862


  2 in total

1.  HMGB1-antagonism exerted by glycyrrhizin could be fruitful against COVID-19.

Authors:  Giorgio Ciprandi; Luisa Maria Bellussi; Valerio Damiani; Desiderio Passali
Journal:  Acta Biomed       Date:  2021-10-01

Review 2.  Research Progress on the Antiviral Activity of Glycyrrhizin and its Derivatives in Liquorice.

Authors:  Changchao Huan; Yao Xu; Wei Zhang; Tingting Guo; Haochun Pan; Song Gao
Journal:  Front Pharmacol       Date:  2021-07-06       Impact factor: 5.810

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.