Tom Shmuly1,2, Yehonatan Ben Zvi3, Gabriel Chaushu2,3, Ilana Kaplan4,5,6. 1. Oral and Maxillofacial Surgery Department, Kaplan Medical Center, Rehovot 7642001, Israel. 2. Oral and Maxillofacial Surgery Department, Goldschleger School of Dental Medicine, Tel-Aviv University, Tel-Aviv 6934206, Israel. 3. Oral and Maxillofacial Surgery Department, Rabin Medical Center, Petah-Tikva 4941492, Israel. 4. Pathology Department, Rabin Medical Center, Petah-Tikva 4941492, Israel. 5. Oral Pathology Department, Goldschleger School of Dental Medicine, Tel-Aviv University, Tel-Aviv 6934206, Israel. 6. Pathology Department, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv 6934206, Israel.
Abstract
Background and Objectives: This was a retrospective single-center study to analyze and describe the clinical and histological features of all cases of oral solitary fibrous tumor (SFT). Study design: the study included all consecutive cases of oral SFT diagnosed between 2008-2018 at a single tertiary center. Materials and Methods: Clinical data was retrieved from medical charts. The diagnosis of oral SFT was based upon the morphologic features of the lesions, in routine hematoxylin and eosin (H&E) stained sections and confirmed by immunohistochemical analyses including CD34, CD99, Bcl2, and stains for STAT6. Results: Seven cases of oral SFT were found. Of these, three (42%) were in males and four (58%) in females. The age range was 24-63 years (mean 47 ± 13). Four (58%) lesions were located in the buccal mucosa, two (28%) in the labial mucosa and one (14%) on the floor of the mouth. The diameter ranged between 3-50 mm (mean 22 ± 14 mm). All patients were treated with local excision. Follow-up periods were between 2-74 months (mean 41 ± 27). No recurrences were reported. Conclusions: We present a series of oral SFT, which were all non-aggressive in presentation and did not recur after conservative surgery (local excision) over a relatively long follow-up period.
Background and Objectives: This was a retrospective single-center study to analyze and describe the clinical and histological features of all cases of oral solitary fibrous tumor (SFT). Study design: the study included all consecutive cases of oral SFT diagnosed between 2008-2018 at a single tertiary center. Materials and Methods: Clinical data was retrieved from medical charts. The diagnosis of oral SFT was based upon the morphologic features of the lesions, in routine hematoxylin and eosin (H&E) stained sections and confirmed by immunohistochemical analyses including CD34, CD99, Bcl2, and stains for STAT6. Results: Seven cases of oral SFT were found. Of these, three (42%) were in males and four (58%) in females. The age range was 24-63 years (mean 47 ± 13). Four (58%) lesions were located in the buccal mucosa, two (28%) in the labial mucosa and one (14%) on the floor of the mouth. The diameter ranged between 3-50 mm (mean 22 ± 14 mm). All patients were treated with local excision. Follow-up periods were between 2-74 months (mean 41 ± 27). No recurrences were reported. Conclusions: We present a series of oral SFT, which were all non-aggressive in presentation and did not recur after conservative surgery (local excision) over a relatively long follow-up period.
Authors: Fernanda Bispo Nunes; Maria Sissa Pereira Sant'Ana; André Myller Barbosa Silva; Michelle Agostini; Nathalie Henriques Silva Canedo; Bruno Augusto Benevenuto de Andrade; Mário José Romañach; Davi Lavareda Corrêa; Ramiro Alejandro Tomasi; Raghu Radhakrishnan; Ricardo Santiago Gomez; Silvia Ferreira de Sousa; Peter A Brennan; Felipe Paiva Fonseca Journal: J Oral Pathol Med Date: 2019-09-15 Impact factor: 4.253
Authors: I Rodriguez; E Ayala; C Caballero; C De Miguel; X Matias-Guiu; A L Cubilla; J Rosai Journal: Am J Surg Pathol Date: 2001-11 Impact factor: 6.394