Literature DB >> 33567593

The Emerging Role of TXNIP in Ischemic and Cardiovascular Diseases; A Novel Marker and Therapeutic Target.

Alison Domingues1, Julia Jolibois1, Perrine Marquet de Rougé1, Valérie Nivet-Antoine1,2.   

Abstract

Thioredoxin interacting protein (TXNIP) is a metabolism- oxidative- and inflammation-related marker induced in cardiovascular diseases and is believed to represent a possible link between metabolism and cellular redox status. TXNIP is a potential biomarker in cardiovascular and ischemic diseases but also a novel identified target for preventive and curative medicine. The goal of this review is to focus on the novelties concerning TXNIP. After an overview in TXNIP involvement in oxidative stress, inflammation and metabolism, the remainder of this review presents the clues used to define TXNIP as a new marker at the genetic, blood, or ischemic site level in the context of cardiovascular and ischemic diseases.

Entities:  

Keywords:  TXNIP; cardiovascular diseases marker; metabolic disorders; oxidative stress; post-ischemic revascularization

Mesh：

Substances：

Year:  2021        PMID： 33567593      PMCID： PMC7914816          DOI： 10.3390/ijms22041693

Source DB:  PubMed          Journal:  Int J Mol Sci        ISSN： 1422-0067            Impact factor:   5.923


  268 in total

Review 1.  NLRP3 has a sweet tooth.

Authors:  Beckley K Davis; Jenny Pan-Yun Ting
Journal:  Nat Immunol       Date:  2010-02       Impact factor: 25.606

2.  Indigo Fruits Ingredient, Aucubin, Protects against LPS-Induced Cardiac Dysfunction in Mice.

Authors:  MingXia Duan; Yuan Yuan; Chen Liu; Zhulan Cai; Qingwen Xie; Tongtong Hu; Qizhu Tang; QingQing Wu
Journal:  J Pharmacol Exp Ther       Date:  2019-08-29       Impact factor: 4.030

3.  Macrophage migration inhibitory factor interacts with thioredoxin-interacting protein and induces NF-κB activity.

Authors:  Mi Jeong Kim; Won Sam Kim; Dong Oh Kim; Jae-Eun Byun; Hangsak Huy; Soo Yun Lee; Hae Young Song; Young-Jun Park; Tae-Don Kim; Suk Ran Yoon; Eun-Ji Choi; Hyunjung Ha; Haiyoung Jung; Inpyo Choi
Journal:  Cell Signal       Date:  2017-03-18       Impact factor: 4.315

Review 4.  The Emerging Role of Thioredoxin-Interacting Protein in Myocardial Ischemia/Reperfusion Injury.

Authors:  Bing F Wang; Jun Yoshioka
Journal:  J Cardiovasc Pharmacol Ther       Date:  2016-11-02       Impact factor: 2.457

5.  Targeting endothelial thioredoxin-interacting protein (TXNIP) protects from metabolic disorder-related impairment of vascular function and post-ischemic revascularisation.

Authors:  Alison Domingues; Catherine Boisson-Vidal; Perrine Marquet de Rouge; Blandine Dizier; Jérémy Sadoine; Virginie Mignon; Emilie Vessières; Daniel Henrion; Virginie Escriou; Pascal Bigey; Catherine Chaussain; David M Smadja; Valérie Nivet-Antoine
Journal:  Angiogenesis       Date:  2020-01-03       Impact factor: 9.596

6.  The structural basis for the negative regulation of thioredoxin by thioredoxin-interacting protein.

Authors:  Jungwon Hwang; Hyun-Woo Suh; Young Ho Jeon; Eunha Hwang; Loi T Nguyen; Jeonghun Yeom; Seung-Goo Lee; Cheolju Lee; Kyung Jin Kim; Beom Sik Kang; Jin-Ok Jeong; Tae-Kwang Oh; Inpyo Choi; Jie-Oh Lee; Myung Hee Kim
Journal:  Nat Commun       Date:  2014       Impact factor: 14.919

7.  Gender and tachycardia: independent modulation of platelet reactivity in patients with atrial fibrillation.

Authors:  Nathan Ek Procter; Jocasta Ball; Doan Tm Ngo; Jeffrey S Isenberg; Elaine M Hylek; Yuliy Y Chirkov; Simon Stewart; John D Horowitz
Journal:  J Geriatr Cardiol       Date:  2016-03       Impact factor: 3.327

8.  Does cardiac resynchronization therapy restore peripheral circulatory homeostasis?

Authors:  Chukwudiebube N Ajaero; Cher-Rin Chong; Nathan E K Procter; Saifei Liu; Yuliy Y Chirkov; Tamila Heresztyn; Wai Ping Alicia Chan; Margaret A Arstall; Andrew D McGavigan; Michael P Frenneaux; John D Horowitz
Journal:  ESC Heart Fail       Date:  2017-10-13

9.  Inhibitor of RAGE and glucose‑induced inflammation in bone marrow mesenchymal stem cells: Effect and mechanism of action.

Authors:  Mengyi Jiang; Xuemei Wang; Pin Wang; Wei Peng; Bo Zhang; Ling Guo
Journal:  Mol Med Rep       Date:  2020-08-07       Impact factor: 2.952

10.  Exosomes Derived From Mesenchymal Stromal Cells Pretreated With Advanced Glycation End Product-Bovine Serum Albumin Inhibit Calcification of Vascular Smooth Muscle Cells.

Authors:  Ying Wang; Wen-Qi Ma; Yi Zhu; Xi-Qiong Han; Naifeng Liu
Journal:  Front Endocrinol (Lausanne)       Date:  2018-09-21       Impact factor: 5.555
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  8 in total

1.  TXNIP knockout improves cardiac function after myocardial infarction by promoting angiogenesis and reducing cardiomyocyte apoptosis.

Authors:  Jin Wang; Xue-Jiao Wang; Yan Zhang; Wen-Juan Shi; Zhan-Dong Lei; Xiang-Ying Jiao
Journal:  Cardiovasc Diagn Ther       Date:  2022-06

2.  Cochlear Marginal Cell Pyroptosis Is Induced by Cisplatin via NLRP3 Inflammasome Activation.

Authors:  Wenting Yu; Shimin Zong; Peng Zhou; Jiahui Wei; Enhao Wang; Ruijie Ming; Hongjun Xiao
Journal:  Front Immunol       Date:  2022-04-20       Impact factor: 8.786

Review 3.  α-Arrestins and Their Functions: From Yeast to Human Health.

Authors:  Kacper Zbieralski; Donata Wawrzycka
Journal:  Int J Mol Sci       Date:  2022-04-30       Impact factor: 6.208

Review 4.  Inflammation, Oxidative Stress, Senescence in Atherosclerosis: Thioredoxine-1 as an Emerging Therapeutic Target.

Authors:  Khadija El Hadri; Rémy Smith; Eric Duplus; Chahrazade El Amri
Journal:  Int J Mol Sci       Date:  2021-12-22       Impact factor: 5.923

Review 5.  The Emerging Role of Metabolism in Brain-Heart Axis: New Challenge for the Therapy and Prevention of Alzheimer Disease. May Thioredoxin Interacting Protein (TXNIP) Play a Role?

Authors:  Lorena Perrone; Mariarosaria Valente
Journal:  Biomolecules       Date:  2021-11-08

6.  Evaluating the Effects of Low Carbohydrate and High Protein Diet on Erectile Function in Rats.

Authors:  Tomoya Kataoka; Junya Hidaka; Jun Suzuki; Taiki Mori; Daigaku Nakamura; Yuji Hotta; Akimasa Sanagawa; Yasuhiro Maeda; Yoko Furukawa-Hibi; Kazunori Kimura
Journal:  Sex Med       Date:  2022-03-05       Impact factor: 2.523

7.  Emerging New Biomarkers for Cardiovascular Disease.

Authors:  Luc Rochette
Journal:  Int J Mol Sci       Date:  2022-03-18       Impact factor: 5.923

Review 8.  Thioredoxin interacting protein, a key molecular switch between oxidative stress and sterile inflammation in cellular response.

Authors:  Islam N Mohamed; Luling Li; Saifudeen Ismael; Tauheed Ishrat; Azza B El-Remessy
Journal:  World J Diabetes       Date:  2021-12-15
  8 in total

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