Si-Ho Kim1, Yu Mi Wi1, Sujin Lim2, Kil-Tae Han3, In-Gyu Bae4. 1. Division of Infectious Diseases, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon 51353, Korea. 2. Department of Pulmonology Diseases, Gyeongsangnam-do Masan Medical Center, Changwon 51264, Korea. 3. Department of Radiology, Gyeongsangnam-do Masan Medical Center, Changwon 51264, Korea. 4. Division of Infectious Diseases, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju 52727, Korea.
Abstract
BACKGROUND: Concerns are arising about the simultaneous occurrence of the coronavirus disease 2019 (COVID-19) pandemic and the influenza epidemic, the so-called "twindemic". In this study, we compared clinical characteristics and chest images from patients with COVID-19 and influenza. METHODS: We conducted a case-control study of COVID-19 and age- and sex-matched influenza patients. Clinical characteristics and chest imaging findings between patients with COVID-19 and matched influenza patient controls were compared. RESULTS: A total of 47 patients were enrolled in each group. Anosmia (14.9%) and ageusia (21.3%) were only observed in COVID-19 patients. There were 31 (66%) and 23 (48.9%) patients with COVID-19 and influenza who had pulmonary lesions confirmed by chest computed tomography (CT), respectively. The interval between symptom onset and pneumonia was significantly longer in patients with COVID-19. Round opacities were more common in images from COVID-19 patients (41.9% vs. 8.7%, p = 0.007), whereas pure consolidation (0% vs. 34.9%, p < 0.001) and pleural effusion (0% vs. 17.4%, p = 0.028) were more common in images from influenza patients. Notably, the difference in the number of involved pulmonary lobes observed on CT and pulmonary fields observed on radiographic images was significantly higher in COVID-19-associated pneumonia than that in influenza-associated pneumonia (2.32 ± 1.14 vs. 1.48 ± 0.99, p = 0.010). CONCLUSIONS: Chest images and thorough review of clinical findings could provide value for proper differential diagnoses of COVID-19 patients, but they are not sufficiently sensitive for initial diagnoses. In addition, chest radiography could underestimate COVID-19 lung involvement because of the lesion characteristics of COVID-19-associated pneumonia.
BACKGROUND: Concerns are arising about the simultaneous occurrence of the coronavirus disease 2019 (COVID-19) pandemic and the influenza epidemic, the so-called "twindemic". In this study, we compared clinical characteristics and chest images from patients with COVID-19 and influenza. METHODS: We conducted a case-control study of COVID-19 and age- and sex-matched influenzapatients. Clinical characteristics and chest imaging findings between patients with COVID-19 and matched influenzapatient controls were compared. RESULTS: A total of 47 patients were enrolled in each group. Anosmia (14.9%) and ageusia (21.3%) were only observed in COVID-19patients. There were 31 (66%) and 23 (48.9%) patients with COVID-19 and influenza who had pulmonary lesions confirmed by chest computed tomography (CT), respectively. The interval between symptom onset and pneumonia was significantly longer in patients with COVID-19. Round opacities were more common in images from COVID-19patients (41.9% vs. 8.7%, p = 0.007), whereas pure consolidation (0% vs. 34.9%, p < 0.001) and pleural effusion (0% vs. 17.4%, p = 0.028) were more common in images from influenzapatients. Notably, the difference in the number of involved pulmonary lobes observed on CT and pulmonary fields observed on radiographic images was significantly higher in COVID-19-associated pneumonia than that in influenza-associated pneumonia (2.32 ± 1.14 vs. 1.48 ± 0.99, p = 0.010). CONCLUSIONS: Chest images and thorough review of clinical findings could provide value for proper differential diagnoses of COVID-19patients, but they are not sufficiently sensitive for initial diagnoses. In addition, chest radiography could underestimate COVID-19 lung involvement because of the lesion characteristics of COVID-19-associated pneumonia.
Authors: Gary B Smith; David R Prytherch; Paul Meredith; Paul E Schmidt; Peter I Featherstone Journal: Resuscitation Date: 2013-01-04 Impact factor: 5.262
Authors: Harrison X Bai; Ben Hsieh; Zeng Xiong; Kasey Halsey; Ji Whae Choi; Thi My Linh Tran; Ian Pan; Lin-Bo Shi; Dong-Cui Wang; Ji Mei; Xiao-Long Jiang; Qiu-Hua Zeng; Thomas K Egglin; Ping-Feng Hu; Saurabh Agarwal; Fang-Fang Xie; Sha Li; Terrance Healey; Michael K Atalay; Wei-Hua Liao Journal: Radiology Date: 2020-03-10 Impact factor: 11.105
Authors: Tim Fischer; Yassir El Baz; Giulia Scanferla; Nicole Graf; Frederike Waldeck; Gian-Reto Kleger; Thomas Frauenfelder; Jens Bremerich; Sabine Schmidt Kobbe; Jean-Luc Pagani; Sebastian Schindera; Anna Conen; Simon Wildermuth; Sebastian Leschka; Carol Strahm; Stephan Waelti; Tobias Johannes Dietrich; Werner C Albrich Journal: Eur J Radiol Open Date: 2022-06-24