Binge Chang1, Qi Yang2, Zhaoyang Fan3, Shuang Xia4,5, Weiwei Xie6,7, Chen Wang1, Song Liu6, Ruowei Tang6, Shengting Chai6, Yu Guo8, Tianyi Qian9. 1. Department of Neurosurgery, Tianjin First Central Hospital, Tianjin, China. 2. Department of Radiology, Xuan Wu Hospital, Capital Medical University, Beijing, China. 3. Cedars-Sinai Medical Center, 8700 Beverly Blvd, Pacific Theatres, Suite 400, Los Angeles, CA, 90048, USA. 4. Department of Radiology, Tianjin First Central Clinical College, Medical University of Tianjin, Tianjin, China. xiashuang77@163.com. 5. Department of Radiology, Tianjin First Central Hospital, School of Medicine, Nankai University, Number 24 of Fukang Road, Nankai District, Tianjin, 300192, China. xiashuang77@163.com. 6. Department of Radiology, Tianjin First Central Clinical College, Medical University of Tianjin, Tianjin, China. 7. Department of Radiology, Fifth Affiliated Hospital of Sun Yat sen University, Zhuhai, Guangdong, China. 8. Department of Radiology, Tianjin First Central Hospital, Tianjin, China. 9. Siemens Healthcare, MR Collaborations NE Asia, Beijing, China.
Abstract
OBJECTIVES: There is close relationship between lenticulostriate arteries (LSAs) and lacunar infarctions (LIs) of the basal ganglia. The study aims to visualize the LSAs using high-resolution vessel wall imaging (VWI) on 3T system and explore the correlation between LSAs and LIs. METHODS: Fifty-six patients with LIs in basal ganglia, and 44 age-matched control patients were enrolled and analyzed retrospectively. The raw VWI images were reformatted into coronal slices in minimum intensity projection for further observation of LSAs. The risk factors of LIs in basal ganglia were analyzed by univariate and multivariate logistic regression. The correlation and linear regression analysis between the LSAs and LIs, ipsilateral MCA-M1 plaques were investigated. RESULTS: The total number (p < 0.01) and length (p < 0.01) of LSAs were statistically different between basal ganglias with and without LIs. The total number of LSAs and ipsilateral MCA-M1 plaques were independently related to LIs in basal ganglias. The mean length of LSAs were negatively correlated with number (r = - 0.33, p = 0.002) and volume (r = - 0.37, p = 0.001) of LIs. Age, drinking history, and mean length of LSAs were associated with LI occurrence in basal ganglia, and mean length of LSAs was correlated with larger volume of LIs. CONCLUSIONS: Number of LSA reduction and ipsilateral MCA-M1 plaques were associated with the presence of LIs in basal ganglias. Age increasing, drinking history, and shorter LSAs were correlated with the increasing of LIs. KEY POINTS: • Patients with LIs tend to have shorter LSAs. • The characteristics of LSAs and ipsilateral MCA-M1 plaques are associated with LIs in basal ganglias. • Age, drinking history, and mean length of LSAs are correlated with LI features in basal ganglias.
OBJECTIVES: There is close relationship between lenticulostriate arteries (LSAs) and lacunar infarctions (LIs) of the basal ganglia. The study aims to visualize the LSAs using high-resolution vessel wall imaging (VWI) on 3T system and explore the correlation between LSAs and LIs. METHODS: Fifty-six patients with LIs in basal ganglia, and 44 age-matched control patients were enrolled and analyzed retrospectively. The raw VWI images were reformatted into coronal slices in minimum intensity projection for further observation of LSAs. The risk factors of LIs in basal ganglia were analyzed by univariate and multivariate logistic regression. The correlation and linear regression analysis between the LSAs and LIs, ipsilateral MCA-M1 plaques were investigated. RESULTS: The total number (p < 0.01) and length (p < 0.01) of LSAs were statistically different between basal ganglias with and without LIs. The total number of LSAs and ipsilateral MCA-M1 plaques were independently related to LIs in basal ganglias. The mean length of LSAs were negatively correlated with number (r = - 0.33, p = 0.002) and volume (r = - 0.37, p = 0.001) of LIs. Age, drinking history, and mean length of LSAs were associated with LI occurrence in basal ganglia, and mean length of LSAs was correlated with larger volume of LIs. CONCLUSIONS: Number of LSA reduction and ipsilateral MCA-M1 plaques were associated with the presence of LIs in basal ganglias. Age increasing, drinking history, and shorter LSAs were correlated with the increasing of LIs. KEY POINTS: • Patients with LIs tend to have shorter LSAs. • The characteristics of LSAs and ipsilateral MCA-M1 plaques are associated with LIs in basal ganglias. • Age, drinking history, and mean length of LSAs are correlated with LI features in basal ganglias.
Authors: Mukul Sharma; Lesly A Pearce; Oscar R Benavente; David C Anderson; Stuart J Connolly; Santiago Palacio; Christopher S Coffey; Robert G Hart Journal: Stroke Date: 2014-08-26 Impact factor: 7.914
Authors: S Okuchi; T Okada; M Ihara; K Gotoh; A Kido; K Fujimoto; A Yamamoto; M Kanagaki; S Tanaka; R Takahashi; K Togashi Journal: AJNR Am J Neuroradiol Date: 2012-10-11 Impact factor: 3.825