Literature DB >> 3356604

New paulomycins produced by Streptomyces paulus.

A D Argoudelis1, L Baczynskyj, W J Haak, W M Knoll, S A Mizsak, F B Shilliday.   

Abstract

Paulomycin A2 (C34H46N2O17S), paulomycin C (C32H42N2O17S), paulomycin D (C31H40N2O17S), paulomycin E (C29H36N2O16S) and paulomycin F (C29H38N2O16S) have been isolated from fermentations of Streptomyces paulus strain 273. The structure of these compounds was determined using NMR and mass spectroscopic techniques. The new paulomycins, like paulomycins A and B (J. Antibiotics 35: 285-294, 1982) are highly active mainly against Gram-positive organisms.

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Year:  1988        PMID: 3356604     DOI: 10.7164/antibiotics.41.157

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  7 in total

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Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
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2.  Bioprospecting of Novel and Bioactive Compounds from Marine Actinomycetes Isolated from South China Sea Sediments.

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Journal:  Curr Microbiol       Date:  2017-09-16       Impact factor: 2.188

3.  Identification and analysis of the paulomycin biosynthetic gene cluster and titer improvement of the paulomycins in Streptomyces paulus NRRL 8115.

Authors:  Jine Li; Zhoujie Xie; Min Wang; Guomin Ai; Yihua Chen
Journal:  PLoS One       Date:  2015-03-30       Impact factor: 3.240

4.  Paulomycin G, a New Natural Product with Cytotoxic Activity against Tumor Cell Lines Produced by Deep-Sea Sediment Derived Micromonospora matsumotoense M-412 from the Avilés Canyon in the Cantabrian Sea.

Authors:  Aida Sarmiento-Vizcaíno; Alfredo F Braña; Ignacio Pérez-Victoria; Jesús Martín; Nuria de Pedro; Mercedes de la Cruz; Caridad Díaz; Francisca Vicente; José L Acuña; Fernando Reyes; Luis A García; Gloria Blanco
Journal:  Mar Drugs       Date:  2017-08-28       Impact factor: 5.118

5.  Activation and identification of five clusters for secondary metabolites in Streptomyces albus J1074.

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6.  New insights into paulomycin biosynthesis pathway in Streptomyces albus J1074 and generation of novel derivatives by combinatorial biosynthesis.

Authors:  Aránzazu González; Miriam Rodríguez; Alfredo F Braña; Carmen Méndez; José A Salas; Carlos Olano
Journal:  Microb Cell Fact       Date:  2016-03-21       Impact factor: 5.328

7.  Novel Bioactive Paulomycin Derivatives Produced by Streptomyces albus J1074.

Authors:  Jorge Fernández-De la Hoz; Carmen Méndez; José A Salas; Carlos Olano
Journal:  Molecules       Date:  2017-10-18       Impact factor: 4.411

  7 in total

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