Literature DB >> 3356469

Nonionic block polymer surfactants enhance immunogenicity of pneumococcal hexasaccharide-protein vaccines.

G J Zigterman1, H Snippe, M Jansze, E B Ernste, M J De Reuver, J M Willers.   

Abstract

Incorporated in oil-in-water emulsions, nonionic block polymer surfactants change the kinetics of generated antibody responses against pneumococcal hexasaccharide-protein conjugates: prolonged immunoglobulin M and immunoglobulin G responses are realized. Nonionic block polymer surfactants favor the immunogenicity of hexasaccharide-protein conjugates in young mice in such a way that a single injection yields long-lasting protection.

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Year:  1988        PMID： 3356469      PMCID： PMC259843          DOI： 10.1128/iai.56.5.1391-1393.1988

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  26 in total

1.  Measurement of the humoral immune response against Streptococcus pneumoniae type 3 capsular polysaccharide and oligosaccharide containing antigens by ELISA and ELISPOT techniques.

Authors:  G J Zigterman; A F Verheul; E B Ernste; R F Rombouts; M J De Reuver; M Jansze; H Snippe; J M Willers
Journal:  J Immunol Methods       Date:  1988-01-21       Impact factor: 2.303

Review 2.  Considerations for formulating the second-generation pneumococcal capsular polysaccharide vaccine with emphasis on the cross-reactive types within groups.

Authors:  J B Robbins; R Austrian; C J Lee; S C Rastogi; G Schiffman; J Henrichsen; P H Mäkelä; C V Broome; R R Facklam; R H Tiesjema
Journal:  J Infect Dis       Date:  1983-12       Impact factor: 5.226

3.  The adjuvant activity of nonionic block polymer surfactants. I. The role of hydrophile-lipophile balance.

Authors:  R Hunter; F Strickland; F Kézdy
Journal:  J Immunol       Date:  1981-09       Impact factor: 5.422

4.  Vaccination against Streptococcus pneumoniae in childhood: lack of demonstrable benefit in young Australian children.

Authors:  R M Douglas; H B Miles
Journal:  J Infect Dis       Date:  1984-06       Impact factor: 5.226

5.  Immunogenic properties in mice of hexasaccharide from the capsular polysaccharide of Streptococcus pneumoniae type 3.

Authors:  H Snippe; A J van Houte; J E van Dam; M J De Reuver; M Jansze; J M Willers
Journal:  Infect Immun       Date:  1983-06       Impact factor: 3.441

6.  Antibody response to pneumococcal vaccination in children younger than five years of age.

Authors:  R M Douglas; J C Paton; S J Duncan; D J Hansman
Journal:  J Infect Dis       Date:  1983-07       Impact factor: 5.226

Review 7.  The epidemiology of pneumococcal disease in infants and children.

Authors:  J O Klein
Journal:  Rev Infect Dis       Date:  1981 Mar-Apr

8.  The adjuvant activity of nonionic block polymer surfactants. II. Antibody formation and inflammation related to the structure of triblock and octablock copolymers.

Authors:  R L Hunter; B Bennett
Journal:  J Immunol       Date:  1984-12       Impact factor: 5.422

9.  Immunomodulating properties of two synthetic adjuvants: dependence upon type of antigen, dose, and time of administration.

Authors:  L A Hilgers; H Snippe; M Jansze; J M Willers
Journal:  Cell Immunol       Date:  1984-07       Impact factor: 4.868

10.  Preparation, characterization, and immunogenicity of Haemophilus influenzae type b polysaccharide-protein conjugates.

Authors:  R Schneerson; O Barrera; A Sutton; J B Robbins
Journal:  J Exp Med       Date:  1980-08-01       Impact factor: 14.307
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  3 in total

Review 1.  Immunogenicity and immunochemistry of Streptococcus pneumoniae capsular polysaccharides.

Authors:  J E van Dam; A Fleer; H Snippe
Journal:  Antonie Van Leeuwenhoek       Date:  1990-06       Impact factor: 2.271

2.  Ability of monophosphoryl lipid A to augment the antibody response of young mice.

Authors:  P J Baker; J R Hiernaux; M B Fauntleroy; P W Stashak; B Prescott; J L Cantrell; J A Rudbach
Journal:  Infect Immun       Date:  1988-12       Impact factor: 3.441

3.  Nonionic block polymer surfactants modulate the humoral immune response against Streptococcus pneumoniae-derived hexasaccharide-protein conjugates.

Authors:  G J Zigterman; K Schotanus; E B Ernste; G J Van Dam; M Jansze; H Snippe; J M Willers
Journal:  Infect Immun       Date:  1989-09       Impact factor: 3.441
  3 in total

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