Literature DB >> 33563902

XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis.

Johan Van Weyenbergh1, Dirk Daelemans2, Eline Boons3, Tatiane C Nogueira3, Tim Dierckx1, Soraya Maria Menezes1, Maarten Jacquemyn3, Sharon Tamir4, Yosef Landesman4, Lourdes Farré5, Achiléa Bittencourt6, Keisuke Kataoka7, Seishi Ogawa7, Robert Snoeck3, Graciela Andrei3.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2021        PMID： 33563902      PMCID： PMC7873181          DOI： 10.1038/s41408-021-00409-3

Source DB:  PubMed          Journal:  Blood Cancer J        ISSN： 2044-5385            Impact factor:   11.037


× No keyword cloud information.
  21 in total

1.  Integrated molecular analysis of adult T cell leukemia/lymphoma.

Authors:  Keisuke Kataoka; Yasunobu Nagata; Akira Kitanaka; Yuichi Shiraishi; Teppei Shimamura; Jun-Ichirou Yasunaga; Yasushi Totoki; Kenichi Chiba; Aiko Sato-Otsubo; Genta Nagae; Ryohei Ishii; Satsuki Muto; Shinichi Kotani; Yosaku Watatani; June Takeda; Masashi Sanada; Hiroko Tanaka; Hiromichi Suzuki; Yusuke Sato; Yusuke Shiozawa; Tetsuichi Yoshizato; Kenichi Yoshida; Hideki Makishima; Masako Iwanaga; Guangyong Ma; Kisato Nosaka; Masakatsu Hishizawa; Hidehiro Itonaga; Yoshitaka Imaizumi; Wataru Munakata; Hideaki Ogasawara; Toshitaka Sato; Ken Sasai; Kenzo Muramoto; Marina Penova; Takahisa Kawaguchi; Hiromi Nakamura; Natsuko Hama; Kotaro Shide; Yoko Kubuki; Tomonori Hidaka; Takuro Kameda; Tsuyoshi Nakamaki; Ken Ishiyama; Shuichi Miyawaki; Sung-Soo Yoon; Kensei Tobinai; Yasushi Miyazaki; Akifumi Takaori-Kondo; Fumihiko Matsuda; Kengo Takeuchi; Osamu Nureki; Hiroyuki Aburatani; Toshiki Watanabe; Tatsuhiro Shibata; Masao Matsuoka; Satoru Miyano; Kazuya Shimoda; Seishi Ogawa
Journal:  Nat Genet       Date:  2015-10-05       Impact factor: 38.330

2.  Meta-analysis on the use of zidovudine and interferon-alfa in adult T-cell leukemia/lymphoma showing improved survival in the leukemic subtypes.

Authors:  Ali Bazarbachi; Yves Plumelle; Juan Carlos Ramos; Patricia Tortevoye; Zaher Otrock; Graham Taylor; Antoine Gessain; William Harrington; Gérard Panelatti; Olivier Hermine
Journal:  J Clin Oncol       Date:  2010-06-28       Impact factor: 44.544

Review 3.  Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation.

Authors:  Masao Matsuoka; Kuan-Teh Jeang
Journal:  Nat Rev Cancer       Date:  2007-04       Impact factor: 60.716

4.  IRF-4 and c-Rel expression in antiviral-resistant adult T-cell leukemia/lymphoma.

Authors:  Juan Carlos Ramos; Phillip Ruiz; Lee Ratner; Isildinha M Reis; Carlos Brites; Celia Pedroso; Gerald E Byrne; Ngoc L Toomey; Valentine Andela; Edward W Harhaj; Izidore S Lossos; William J Harrington
Journal:  Blood       Date:  2007-04-01       Impact factor: 22.113

Review 5.  Adult T-cell leukemia: molecular basis for clonal expansion and transformation of HTLV-1-infected T cells.

Authors:  Toshiki Watanabe
Journal:  Blood       Date:  2017-01-23       Impact factor: 22.113

6.  Selective inhibitors of nuclear export show that CRM1/XPO1 is a target in chronic lymphocytic leukemia.

Authors:  Rosa Lapalombella; Qingxiang Sun; Katie Williams; Larissa Tangeman; Shruti Jha; Yiming Zhong; Virginia Goettl; Emilia Mahoney; Caroline Berglund; Sneha Gupta; Alicia Farmer; Rajeswaran Mani; Amy J Johnson; David Lucas; Xiaokui Mo; Dirk Daelemans; Vincent Sandanayaka; Sharon Shechter; Dilara McCauley; Sharon Shacham; Michael Kauffman; Yuh Min Chook; John C Byrd
Journal:  Blood       Date:  2012-10-03       Impact factor: 22.113

7.  Inhibition of Crm1-p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ation.

Authors:  Masayuki Kanai; Kazuhiko Hanashiro; Song-Hee Kim; Shuji Hanai; A Hamid Boulares; Masanao Miwa; Kenji Fukasawa
Journal:  Nat Cell Biol       Date:  2007-09-23       Impact factor: 28.824

8.  Inhibition of the CRM1-mediated nucleocytoplasmic transport by N-azolylacrylates: structure-activity relationship and mechanism of action.

Authors:  Tine Van Neck; Christophe Pannecouque; Els Vanstreels; Miguel Stevens; Wim Dehaen; Dirk Daelemans
Journal:  Bioorg Med Chem       Date:  2008-09-20       Impact factor: 3.641

9.  IFN-β induces greater antiproliferative and proapoptotic effects and increased p53 signaling compared with IFN-α in PBMCs of Adult T-cell Leukemia/Lymphoma patients.

Authors:  T Dierckx; R Khouri; S M Menezes; D Decanine; L Farre; A Bittencourt; A M Vandamme; J Van Weyenbergh
Journal:  Blood Cancer J       Date:  2017-01-27       Impact factor: 11.037

10.  Interferon regulatory factor 4 as a therapeutic target in adult T-cell leukemia lymphoma.

Authors:  Daniel A Rauch; Sydney L Olson; John C Harding; Hemalatha Sundaramoorthi; Youngsoo Kim; Tianyuan Zhou; A Robert MacLeod; Grant Challen; Lee Ratner
Journal:  Retrovirology       Date:  2020-08-28       Impact factor: 4.602
View more
  2 in total

1.  Anti-Osteoclast Effect of Exportin-1 Inhibitor Eltanexor on Osteoporosis Depends on Nuclear Accumulation of IκBα-NF-κB p65 Complex.

Authors:  Junchun Chen; Dezhi Song; Yang Xu; Liwei Wu; Lili Tang; YuanGang Su; Xiaoxiao Xie; Jinmin Zhao; Jiake Xu; Qian Liu
Journal:  Front Pharmacol       Date:  2022-08-30       Impact factor: 5.988

2.  Inhibition of XPO1 with KPT-330 induces autophagy-dependent apoptosis in gallbladder cancer by activating the p53/mTOR pathway.

Authors:  Cheng Zhao; Zi-Yi Yang; Jian Zhang; Ou Li; Shi-Lei Liu; Chen Cai; Yi-Jun Shu; Li-Jia Pan; Wei Gong; Ping Dong
Journal:  J Transl Med       Date:  2022-09-30       Impact factor: 8.440
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.