Literature DB >> 33560251

No Difference in Functional Outcome but Higher Revision Rate Among Smokers Undergoing Cervical Artificial Disc Replacement: Analysis of a Spine Registry.

Lee Wen-Shen1,2, Maksim Lai Wern Sheng1, William Yeo3, Tan Seang Beng1, Yue Wai Mun1, Guo Chang Ming1, Mohammad Mashfiqul Arafin Siddiqui1.   

Abstract

BACKGROUND: Smoking is a known predictor of negative outcomes in spinal surgery. However, its effect on the functional outcomes and revision rates after ADR is not well-documented. This study is a retrospective analysis of prospectively collected data at a major tertiary center. The objective was to elucidate the impact of smoking on functional outcomes in cervical artificial disc replacement (ADR).
METHODS: Patients who underwent cervical ADR for myelopathy or radiculopathy from 2004 to 2015 with a minimum of 2 years of follow-up were included in the study. Patient function was assessed using Short Form-36 (SF-36), American Association of Orthopaedic Surgery (AAOS) cervical spine, and Japanese Orthopaedic Association (JOA) scoring systems preoperatively and at 2 years postoperatively. Incidence of further surgery on affected and adjacent segments was analyzed as well.
RESULTS: A total of 137 patients were included in the study, consisting of 117 nonsmokers and 20 smokers. There were 60 patients who presented with myelopathy and 77 with radiculopathy. The mean age of smokers was 42.6 years, compared with 46.4 years in the nonsmoker group (P < .01). Statistical improvement was noted in postoperative range of motion, as well as AAOS, SF-36, and JOA scores in both groups, with no difference between groups at 2 years of follow-up. A total of 84.2% of nonsmokers and 87.5% of smokers reported as surgery having met their expectations. A total of 5 of 117 nonsmokers (5.1%) and 4 of 20 smokers (20%) needed revision surgery (P = .018). Three of the 4 smokers who required surgery for adjacent or multisegment disease, whereas only 2 of the nonsmokers needed an operation for adjacent segment disease.
CONCLUSIONS: Our analysis indicates that there is no difference in functional outcome or patient satisfaction between smokers and nonsmokers. Smokers have a higher chance of revision surgery after an artificial disc replacement compared with nonsmokers at 2 years. LEVEL OF EVIDENCE: 3. This manuscript is generously published free of charge by ISASS, the International Society for the Advancement of Spine Surgery.
Copyright © 2020 ISASS.

Entities:  

Keywords:  anterior cervical discectomy and fusion; artificial disc replacement; cervical spine; functional outcome; fusion; myelopathy; radiculopathy; revision; smoking; spine

Year:  2020        PMID: 33560251      PMCID: PMC7872401          DOI: 10.14444/7140

Source DB:  PubMed          Journal:  Int J Spine Surg        ISSN: 2211-4599


  26 in total

1.  Biomechanical testing of an artificial cervical joint and an anterior cervical plate.

Authors:  Denis J DiAngelo; James T Roberston; Newton H Metcalf; Bobby J McVay; R Champ Davis
Journal:  J Spinal Disord Tech       Date:  2003-08

2.  Does smoking have an impact on fusion rate in single-level anterior cervical discectomy and fusion with allograft and rigid plate fixation? Clinical article.

Authors:  Myles Luszczyk; Justin S Smith; Jeffrey S Fischgrund; Steven C Ludwig; Rick C Sasso; Christopher I Shaffrey; Alexander R Vaccaro
Journal:  J Neurosurg Spine       Date:  2013-08-30

3.  Risk factors for persistent dysphagia after anterior cervical spine surgery.

Authors:  Erik C Olsson; Meghan Jobson; Moe R Lim
Journal:  Orthopedics       Date:  2015-04       Impact factor: 1.390

4.  Tobacco exposure and wound healing in head and neck surgical wounds.

Authors:  Amy Anne D Lassig; Joan E Bechtold; Bruce R Lindgren; Andrew Pisansky; Abayo Itabiyi; Bevan Yueh; Anne M Joseph
Journal:  Laryngoscope       Date:  2017-09-20       Impact factor: 3.325

Review 5.  Cervical radiculopathy: epidemiology, etiology, diagnosis, and treatment.

Authors:  Barrett I Woods; Alan S Hilibrand
Journal:  J Spinal Disord Tech       Date:  2015-06

Review 6.  Mechanical and cellular processes driving cervical myelopathy.

Authors:  Roisin T Dolan; Joseph S Butler; John M O'Byrne; Ashley R Poynton
Journal:  World J Orthop       Date:  2016-01-18

Review 7.  Anterior cervical spine surgery-associated complications in a retrospective case-control study.

Authors:  Anastasia Tasiou; Theofanis Giannis; Alexandros G Brotis; Ioannis Siasios; Iordanis Georgiadis; Haralampos Gatos; Eleni Tsianaka; Konstantinos Vagkopoulos; Konstantinos Paterakis; Kostas N Fountas
Journal:  J Spine Surg       Date:  2017-09

Review 8.  Degenerative cervical spondylosis: clinical syndromes, pathogenesis, and management.

Authors:  Raj D Rao; Bradford L Currier; Todd J Albert; Christopher M Bono; Satyajit V Marawar; Kornelis A Poelstra; Jason C Eck
Journal:  Instr Course Lect       Date:  2008

Review 9.  Mid- to Long-Term Outcomes of Cervical Disc Arthroplasty versus Anterior Cervical Discectomy and Fusion for Treatment of Symptomatic Cervical Disc Disease: A Systematic Review and Meta-Analysis of Eight Prospective Randomized Controlled Trials.

Authors:  Yan Hu; Guohua Lv; Siying Ren; Daniel Johansen
Journal:  PLoS One       Date:  2016-02-12       Impact factor: 3.240

10.  Discover cervical disc arthroplasty versus anterior cervical discectomy and fusion in symptomatic cervical disc diseases: A meta-analysis.

Authors:  Lei Shangguan; Guang-Zhi Ning; Yu Tang; Zhe Wang; Zhuo-Jing Luo; Yue Zhou
Journal:  PLoS One       Date:  2017-03-30       Impact factor: 3.240

View more
  1 in total

1.  Relationship between smoking and postoperative complications of cervical spine surgery: a systematic review and meta-analysis.

Authors:  Li-Ming Zheng; Zhi-Wen Zhang; Wei Wang; Yang Li; Feng Wen
Journal:  Sci Rep       Date:  2022-06-02       Impact factor: 4.996

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.