Literature DB >> 3355782

Recovery of cutaneous immune responsiveness after PUVA therapy.

S I White1, P S Friedmann, C Moss, J M Simpson.   

Abstract

We studied sensitization to dinitrochlorobenzene (DNCB) in psoriatic patients before, during and 2, 4, and 6 weeks after a course of photochemotherapy (PUVA). The inhibition of sensitivity observed during PUVA was completely reversed after 6 weeks. Thus the PUVA-mediated inhibition of cutaneous immune responsiveness is of short duration. However, whether there are long-term sequelae remains to be established.

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Year:  1988        PMID: 3355782     DOI: 10.1111/j.1365-2133.1988.tb02435.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  1 in total

1.  Antigenic stimulation during ultraviolet therapy in man does not result in immunological tolerance.

Authors:  P S Friedmann; S I White; S Parker; C Moss; J N Matthews
Journal:  Clin Exp Immunol       Date:  1989-04       Impact factor: 4.330

  1 in total

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