Literature DB >> 33557277

Challenges to Bringing Personalized Medicine to a Low-Resource Setting in Peru.

Nelly Solis1, Elizabeth Zavaleta1, Patrik Wernhoff2, Constantino Dominguez-Barrera3, Mev Dominguez-Valentin4.   

Abstract

We provide an overview of the challenges that low-resource setting cities are facing, including a lack of global implementation of cancer screening programs, accurate data and statistics that may aid the health authorities and guide future public health activities, as well as reorient strategies, interventions and budgets to promote lifestyles that help prevent disease. Current cancer care does not fully reflect ethnic, cultural, environmental and resource differences. Herein, we described a snapshot of the cancer mortality and morbidity from a hospital that cares a rural and low-income population from Peru, called Chimbote (316,966 inhabitants) and showed the limitation of access to oncological care and genetic services. The city is located in the region of Ancash, which is a department of Northern Peru. Of note, we identified a greater proportion of cancer cases than previously described, with a young age of onset and differential profile of the most frequent cancers. With the emergence of increasingly effective interventions, it becomes paramount that populations living in resource-limited settings have access to cancer services and participate in genetics and genomic research.

Entities:  

Keywords:  low-resource setting; precision medicine; vulnerable population

Year:  2021        PMID: 33557277      PMCID: PMC7922680          DOI: 10.3390/ijerph18041470

Source DB:  PubMed          Journal:  Int J Environ Res Public Health        ISSN: 1660-4601            Impact factor:   3.390


  14 in total

Review 1.  Genetic diversity in populations across Latin America: implications for population and medical genetic studies.

Authors:  Gillian M Belbin; Maria A Nieves-Colón; Eimear E Kenny; Andres Moreno-Estrada; Christopher R Gignoux
Journal:  Curr Opin Genet Dev       Date:  2018-08-17       Impact factor: 5.578

2.  Planning cancer control in Latin America and the Caribbean.

Authors:  Paul E Goss; Brittany L Lee; Tanja Badovinac-Crnjevic; Kathrin Strasser-Weippl; Yanin Chavarri-Guerra; Jessica St Louis; Cynthia Villarreal-Garza; Karla Unger-Saldaña; Mayra Ferreyra; Márcio Debiasi; Pedro E R Liedke; Diego Touya; Gustavo Werutsky; Michaela Higgins; Lei Fan; Claudia Vasconcelos; Eduardo Cazap; Carlos Vallejos; Alejandro Mohar; Felicia Knaul; Hector Arreola; Rekha Batura; Silvana Luciani; Richard Sullivan; Dianne Finkelstein; Sergio Simon; Carlos Barrios; Rebecca Kightlinger; Andres Gelrud; Vladimir Bychkovsky; Gilberto Lopes; Stephen Stefani; Marcelo Blaya; Fabiano Hahn Souza; Franklin Santana Santos; Alberto Kaemmerer; Evandro de Azambuja; Andres Felipe Cardona Zorilla; Raul Murillo; Jose Jeronimo; Vivien Tsu; Andre Carvalho; Carlos Ferreira Gil; Cinthya Sternberg; Alfonso Dueñas-Gonzalez; Dennis Sgroi; Mauricio Cuello; Rodrigo Fresco; Rui Manuel Reis; Guiseppe Masera; Raúl Gabús; Raul Ribeiro; Renata Knust; Gustavo Ismael; Eduardo Rosenblatt; Berta Roth; Luisa Villa; Argelia Lara Solares; Marta Ximena Leon; Isabel Torres-Vigil; Alfredo Covarrubias-Gomez; Andrés Hernández; Mariela Bertolino; Gilberto Schwartsmann; Sergio Santillana; Francisco Esteva; Luis Fein; Max Mano; Henry Gomez; Marc Hurlbert; Alessandra Durstine; Gustavo Azenha
Journal:  Lancet Oncol       Date:  2013-04       Impact factor: 41.316

3.  Cancer patterns, trends and projections in Latin America and the Caribbean: a global context.

Authors:  Freddie Bray; Marion Piñeros
Journal:  Salud Publica Mex       Date:  2016-04

Review 4.  Cancer burden in Latin America and the Caribbean.

Authors:  Maria Paula Curado; Dyego Leandro Bezerra de Souza
Journal:  Ann Glob Health       Date:  2014 Sep-Oct       Impact factor: 2.462

5.  Cáncer colorrectal en los jóvenes: factores pronósticos y características clínico patológicas en un instituto del cáncer de Perú.

Authors:  Rossana Ruiz; Luis Taxa; Eloy F Ruiz; Raúl Mantilla; Luis Casanova; Paola Montenegro
Journal:  Rev Gastroenterol Peru       Date:  2016 Jan-Mar

Review 6.  Multiple primary cancers as a guide to heritability.

Authors:  Cezary Cybulski; Safia Nazarali; Steven A Narod
Journal:  Int J Cancer       Date:  2014-06-19       Impact factor: 7.396

Review 7.  Cancer patterns, trends, and transitions in Peru: a regional perspective.

Authors:  Marion Piñeros; Willy Ramos; Sébastien Antoni; Graciela Abriata; Luis E Medina; J Jaime Miranda; Eduardo Payet; Freddie Bray
Journal:  Lancet Oncol       Date:  2017-10       Impact factor: 41.316

Review 8.  Screening for cancer in low- and middle-income countries.

Authors:  R Sankaranarayanan
Journal:  Ann Glob Health       Date:  2014 Sep-Oct       Impact factor: 2.462

9.  A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America.

Authors:  Benedito Mauro Rossi; Edenir Inêz Palmero; Francisco López-Kostner; Carlos Sarroca; Carlos Alberto Vaccaro; Florencia Spirandelli; Patricia Ashton-Prolla; Yenni Rodriguez; Henrique de Campos Reis Galvão; Rui Manuel Reis; André Escremim de Paula; Luis Gustavo Capochin Romagnolo; Karin Alvarez; Adriana Della Valle; Florencia Neffa; Pablo German Kalfayan; Enrique Spirandelli; Sergio Chialina; Melva Gutiérrez Angulo; Maria Del Carmen Castro-Mujica; Julio Sanchez de Monte; Richard Quispe; Sabrina Daniela da Silva; Norma Teresa Rossi; Claudia Barletta-Carrillo; Susana Revollo; Ximena Taborga; L Lena Morillas; Hélène Tubeuf; Erika Maria Monteiro-Santos; Tamara Alejandra Piñero; Constantino Dominguez-Barrera; Patrik Wernhoff; Alexandra Martins; Eivind Hovig; Pål Møller; Mev Dominguez-Valentin
Journal:  BMC Cancer       Date:  2017-09-05       Impact factor: 4.430

10.  Cancer mortality predictions for 2017 in Latin America.

Authors:  G Carioli; C La Vecchia; P Bertuccio; T Rodriguez; F Levi; P Boffetta; E Negri; M Malvezzi
Journal:  Ann Oncol       Date:  2017-09-01       Impact factor: 32.976

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