Literature DB >> 33557077

The Application of Seaweed Polysaccharides and Their Derived Products with Potential for the Treatment of Alzheimer's Disease.

Sarah Bauer1, Weihua Jin1,2, Fuming Zhang3, Robert J Linhardt1,3,4.   

Abstract

Neurodegenerative diseases are among the most widespread diseases affecting humans, and the number of patients is only rising. Seaweed polysaccharide extracts show significant neuroprotective and reparative activities. Seaweed polysaccharides might provide the next big breakthrough in neurodegenerative disease treatment. This paper reviews the applications of seaweed polysaccharides as potential treatments of neurodegenerative diseases. The particular focus is on fucoidan, ulvan, and their derivatives as potential agents to treat Alzheimer's disease. This review provides a critical update on the progress in this important research area.

Entities:  

Keywords:  Alzheimer’s disease; neuroprotective activity; polysaccharides; seaweeds

Mesh：

Substances：

Year:  2021        PMID： 33557077      PMCID： PMC7913876          DOI： 10.3390/md19020089

Source DB:  PubMed          Journal:  Mar Drugs        ISSN： 1660-3397            Impact factor:   5.118


  34 in total

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Authors:  Hasnaa A Elfawy; Biswadeep Das
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Review 2.  Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases.

Authors:  Michael T Lin; M Flint Beal
Journal:  Nature       Date:  2006-10-19       Impact factor: 49.962

3.  Alginate Oligosaccharides: Production, Biological Activities, and Potential Applications.

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4.  Highly stabilized curcumin nanoparticles tested in an in vitro blood-brain barrier model and in Alzheimer's disease Tg2576 mice.

Authors:  Kwok Kin Cheng; Chin Fung Yeung; Shuk Wai Ho; Shing Fung Chow; Albert H L Chow; Larry Baum
Journal:  AAPS J       Date:  2012-12-11       Impact factor: 4.009

5.  Cholinesterase inhibitors for the treatment of Alzheimer's disease:: getting on and staying on.

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Review 6.  Bioengineered 3D Glial Cell Culture Systems and Applications for Neurodegeneration and Neuroinflammation.

Authors:  P Marc D Watson; Edel Kavanagh; Gary Allenby; Matthew Vassey
Journal:  SLAS Discov       Date:  2017-02-21       Impact factor: 3.341

7.  Adding Chinese herbal medicine to conventional therapy brings cognitive benefits to patients with Alzheimer's disease: a retrospective analysis.

Authors:  Jing Shi; Jingnian Ni; Tao Lu; Xuekai Zhang; Mingqing Wei; Ting Li; Weiwei Liu; Yongyan Wang; Yuanyuan Shi; Jinzhou Tian
Journal:  BMC Complement Altern Med       Date:  2017-12-13       Impact factor: 3.659

Review 8.  Food-Derived Antioxidant Polysaccharides and Their Pharmacological Potential in Neurodegenerative Diseases.

Authors:  Haifeng Li; Fei Ding; Lingyun Xiao; Ruona Shi; Hongyu Wang; Wenjing Han; Zebo Huang
Journal:  Nutrients       Date:  2017-07-19       Impact factor: 5.717

9.  Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression.

Authors:  Xinyi Wang; Guangqiang Sun; Teng Feng; Jing Zhang; Xun Huang; Tao Wang; Zuoquan Xie; Xingkun Chu; Jun Yang; Huan Wang; Shuaishuai Chang; Yanxue Gong; Lingfei Ruan; Guanqun Zhang; Siyuan Yan; Wen Lian; Chen Du; Dabing Yang; Qingli Zhang; Feifei Lin; Jia Liu; Haiyan Zhang; Changrong Ge; Shifu Xiao; Jian Ding; Meiyu Geng
Journal:  Cell Res       Date:  2019-09-06       Impact factor: 25.617

10.  Quantitative Assessment of Hippocampal Tau Pathology in AD and PART.

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Journal:  J Mol Neurosci       Date:  2020-05-05       Impact factor: 3.444
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  11 in total

Review 1.  Phytochemical and Potential Properties of Seaweeds and Their Recent Applications: A Review.

Authors:  Hossam S El-Beltagi; Amal A Mohamed; Heba I Mohamed; Khaled M A Ramadan; Aminah A Barqawi; Abdallah Tageldein Mansour
Journal:  Mar Drugs       Date:  2022-05-24       Impact factor: 6.085

Review 2.  Role of Environmental Toxicants on Neurodegenerative Disorders.

Authors:  Masarat Nabi; Nahida Tabassum
Journal:  Front Toxicol       Date:  2022-05-11

3.  Fucoidan Modulated Oxidative Stress and Caspase-3 mRNA Expression Induced by Sulfoxaflor in the Brain of Mice.

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Journal:  Neurotox Res       Date:  2021-09-27       Impact factor: 3.911

Review 4.  An Overview to the Health Benefits of Seaweeds Consumption.

Authors:  Silvia Lomartire; João Carlos Marques; Ana M M Gonçalves
Journal:  Mar Drugs       Date:  2021-06-15       Impact factor: 5.118

Review 5.  The Seaweed Diet in Prevention and Treatment of the Neurodegenerative Diseases.

Authors:  Leonel Pereira; Ana Valado
Journal:  Mar Drugs       Date:  2021-02-26       Impact factor: 5.118

Review 6.  Therapeutic Potential and Nutraceutical Profiling of North Bornean Seaweeds: A Review.

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Journal:  Mar Drugs       Date:  2022-01-25       Impact factor: 5.118

Review 7.  Microalgal Biorefinery Concepts' Developments for Biofuel and Bioproducts: Current Perspective and Bottlenecks.

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Review 8.  Alzheimer's Disease and Toxins Produced by Marine Dinoflagellates: An Issue to Explore.

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9.  Characterization of Novel Selected Microalgae for Antioxidant Activity and Polyphenols, Amino Acids, and Carbohydrates.

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Journal:  Mar Drugs       Date:  2021-12-30       Impact factor: 5.118

Review 10.  Marine Algae-Derived Bioactive Compounds: A New Wave of Nanodrugs?

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Journal:  Mar Drugs       Date:  2021-08-26       Impact factor: 5.118
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