Lack of alcohol-deprivation effect in AA rats.

Rats that have had at least several weeks of access to ethanol generally react to a week or more without it by drinking more alcohol on the first few days of renewed access. This alcohol-deprivation effect was again seen now in 25 male Long-Evans rats but not in 21 males of the heavy-drinking AA line. The present results obtained with F51 generation AAs differ from ones obtained previously with F32 AAs, which showed an initially small but long-lasting increase after deprivation, and may indicate a change produced by the intervening revitalization of the AA line.