| Literature DB >> 33555616 |
William Ak-Lam Lo1, Daniel Ki-Yan Mak2, Michael Ming-Cheuk Wong3, Oi-Wah Chan4, Eileena Mo-Ching Chui5, Dicky Wai-Sau Chung2, Glendy Suk-Han Ip1, Ka-Shing Lau6, Che-Kin Lee7, Jolene Mui8, Ka-Lok Tam2, Samson Tse5, Kwong-Lui Wong9.
Abstract
Recent research on second-generation long-acting injectable antipsychotics (LAI SGAs) has proven its effectiveness in minimizing medication nonadherence problem and reducing relapses. Administered by medical professionals, making quick detection of nonadherence possible, long-acting injectable antipsychotics (LAIs) facilitate immediate intervention and recovery process, and thus are favored by psychiatrists. Despite a higher initial cost with LAIs, the subsequent schizophrenia-related health costs for hospitalizations and outpatients are greatly reduced. With reference to guidelines published by psychiatric associations around the globe, this article looks at scenarios in Hong Kong on the management of severe mentally ill patients with regard to the use of a host of psychosocial interventions as well as LAI SGAs as a preferable treatment. In particular, it examines the benefits of using LAI SGAs for Hong Kong patients who demonstrated high nonadherence treatment rates due to their social environment. It assesses the rationale behind the early usages of LAI SGAs, which help to provide better recovery outcomes for patients.Entities:
Keywords: Hong Kong; antipsychotic agents; paliperidone palmitate; patient compliance; schizophrenia
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Year: 2021 PMID: 33555616 PMCID: PMC7869929 DOI: 10.1111/cns.13375
Source DB: PubMed Journal: CNS Neurosci Ther ISSN: 1755-5930 Impact factor: 5.243