Literature DB >> 33552880

Simultaneous debridement, Ilizarov reconstruction and free muscle flaps in the management of complex tibial infection.

Max Mifsud1, Jamie Y Ferguson1, David A Stubbs1, Alex J Ramsden1, Martin A McNally1.   

Abstract

Chronic bone infections often present with complex bone and soft tissue loss. Management is difficult and commonly delivered in multiple stages over many months. This study investigated the feasibility and clinical outcomes of reconstruction in one stage. Fifty-seven consecutive patients with chronic osteomyelitis ( n = 27 ) or infected non-union ( n = 30 ) were treated with simultaneous debridement, Ilizarov method and free muscle flap transfer. 41 patients (71.9 %) had systemic co-morbidities (Cierny-Mader group Bs hosts). Infection was confirmed with strict criteria. 48 patients (84.2 %) had segmental defects. The primary outcome was eradication of infection at final follow-up. Secondary outcomes included bone union, flap survival and complications or re-operation related to the reconstruction. Infection was eradicated in 55 / 57 cases (96.5 %) at a mean follow-up of 36 months (range 12-146). No flap failures occurred during distraction but 6 required early anastomotic revision and 3 were not salvageable (flap failure rate 5.3 %). Bony union was achieved in 52 / 57 (91.2 %) with the initial surgery alone. After treatment of the five un-united docking sites, all cases achieved bony union at final follow-up. Simultaneous reconstruction with Ilizarov method and free tissue transfer is safe but requires careful planning and logistic considerations. The outcomes from this study are equivalent or better than those reported after staged surgery. Copyright:
© 2020 Max Mifsud et al.

Entities:  

Year:  2020        PMID: 33552880      PMCID: PMC7852407          DOI: 10.5194/jbji-6-63-2020

Source DB:  PubMed          Journal:  J Bone Jt Infect        ISSN: 2206-3552


  37 in total

1.  Bone transport versus acute shortening for the management of infected tibial non-unions with bone defects.

Authors:  Kevin Tetsworth; Dror Paley; Cengiz Sen; Matthew Jaffe; Dean C Maar; Vaida Glatt; Erik Hohmann; John E Herzenberg
Journal:  Injury       Date:  2017-07-12       Impact factor: 2.586

2.  Management of infected nonunion of the long bones by a multidisciplinary team.

Authors:  D Bose; R Kugan; D Stubbs; M McNally
Journal:  Bone Joint J       Date:  2015-06       Impact factor: 5.082

3.  Single-stage treatment of chronic osteomyelitis with a new absorbable, gentamicin-loaded, calcium sulphate/hydroxyapatite biocomposite: a prospective series of 100 cases.

Authors:  M A McNally; J Y Ferguson; A C K Lau; M Diefenbeck; M Scarborough; A J Ramsden; B L Atkins
Journal:  Bone Joint J       Date:  2016-09       Impact factor: 5.082

4.  Getting it right first time: The importance of a structured tissue sampling protocol for diagnosing fracture-related infections.

Authors:  P Hellebrekers; R J Rentenaar; M A McNally; F Hietbrink; R M Houwert; L P H Leenen; G A M Govaert
Journal:  Injury       Date:  2019-06-07       Impact factor: 2.586

5.  Long-term results and costs of muscle flap coverage with Ilizarov bone transport in lower limb salvage.

Authors:  David W Lowenberg; Rudolf F Buntic; Gregory M Buncke; Brian M Parrett
Journal:  J Orthop Trauma       Date:  2013-10       Impact factor: 2.512

6.  Is acute compression and distraction superior to segmental bone transport techniques in chronic tibial osteomyelitis ? Comparison of Distraction Osteogenesis Techniques.

Authors:  L Eralp; M Kocaoglu; M Celiktas; M Gülşen
Journal:  Acta Orthop Belg       Date:  2016-09       Impact factor: 0.500

7.  A dedicated team approach enhances outcomes of osteomyelitis treatment.

Authors:  Bruce H Ziran; Nalini Rao; Ronald A Hall
Journal:  Clin Orthop Relat Res       Date:  2003-09       Impact factor: 4.176

8.  The use of a biodegradable antibiotic-loaded calcium sulphate carrier containing tobramycin for the treatment of chronic osteomyelitis: a series of 195 cases.

Authors:  J Y Ferguson; M Dudareva; N D Riley; D Stubbs; B L Atkins; M A McNally
Journal:  Bone Joint J       Date:  2014-06       Impact factor: 5.082

Review 9.  Management of Post-Traumatic Osteomyelitis in the Lower Limb: Current State of the Art.

Authors:  James K K Chan; Jamie Y Ferguson; Matthew Scarborough; Martin A McNally; Alex J Ramsden
Journal:  Indian J Plast Surg       Date:  2019-04-29

10.  Costs and renumeration of osteomyelitis treatment involving free flaps: implications of return to theatre.

Authors:  Rebecca Shirley; Janka Fazekas; Martin McNally; Alex Ramsden
Journal:  J Bone Jt Infect       Date:  2018-02-05
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  2 in total

1.  Three-stage limb salvage in tibial fracture related infection with composite bone and soft-tissue defect.

Authors:  Pablo S Corona; Carla Carbonell-Rosell; Matías Vicente; Jordi Serracanta; Kevin Tetsworth; Vaida Glatt
Journal:  Arch Orthop Trauma Surg       Date:  2021-12-22       Impact factor: 3.067

Review 2.  A systematic review of phage therapy applied to bone and joint infections: an analysis of success rates, treatment modalities and safety.

Authors:  Joseph Genevière; Shawna McCallin; Angela Huttner; Truong-Thanh Pham; Domizio Suva
Journal:  EFORT Open Rev       Date:  2021-12-10
  2 in total

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