Literature DB >> 33552773

An Atypical Case of COVID-19 Induced Pancytopenia, Rhabdomyolysis and Myocarditis.

Olusayo Fadiran1.   

Abstract

Severe acute respiratory distress coronavirus 2 (SARS-CoV-2) virus is responsible for the current pandemic - coronavirus disease 2019 (COVID-19) plaguing the world. It began spreading as early as January 2020 in the United States (US) and has recently become the leading cause of death amongst adults over 45 years of age. Much of its clinical presentation is already known, and there have been advances in its successful treatment with a food and drug administration (FDA) approved antiviral medication called remdesivir, and other proven investigational methods with clinical benefits including dexamethasone and COVID-19 antibody transfusion called convalescent plasma therapy. However, the recommendations for their use include COVID-19 confirmed patients requiring supplemental oxygen or other forms of respiratory support. In this case report, we describe in detail a unique case of severe COVID-19 infection that did not require any form of oxygen support but was treated successfully with antiviral medications and steroids. The purpose of this report is to highlight in detail an unusual COVID-19 presentation with rhabdomyolysis, myocarditis, and pancytopenia severe enough to require hospitalization and treatment with proven COVID-19 therapy to achieve clinical resolution.
Copyright © 2021, Fadiran et al.

Entities:  

Keywords:  covid and myocarditis; covid-19; rhabdomyolysis; “pancytopenia”

Year:  2021        PMID: 33552773      PMCID: PMC7853727          DOI: 10.7759/cureus.12455

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  19 in total

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Review 3.  Highlight of Immune Pathogenic Response and Hematopathologic Effect in SARS-CoV, MERS-CoV, and SARS-Cov-2 Infection.

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Journal:  Front Immunol       Date:  2020-05-12       Impact factor: 7.561

4.  Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial.

Authors:  Yeming Wang; Dingyu Zhang; Guanhua Du; Ronghui Du; Jianping Zhao; Yang Jin; Shouzhi Fu; Ling Gao; Zhenshun Cheng; Qiaofa Lu; Yi Hu; Guangwei Luo; Ke Wang; Yang Lu; Huadong Li; Shuzhen Wang; Shunan Ruan; Chengqing Yang; Chunlin Mei; Yi Wang; Dan Ding; Feng Wu; Xin Tang; Xianzhi Ye; Yingchun Ye; Bing Liu; Jie Yang; Wen Yin; Aili Wang; Guohui Fan; Fei Zhou; Zhibo Liu; Xiaoying Gu; Jiuyang Xu; Lianhan Shang; Yi Zhang; Lianjun Cao; Tingting Guo; Yan Wan; Hong Qin; Yushen Jiang; Thomas Jaki; Frederick G Hayden; Peter W Horby; Bin Cao; Chen Wang
Journal:  Lancet       Date:  2020-04-29       Impact factor: 79.321

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Authors:  Chen Wang; Peter W Horby; Frederick G Hayden; George F Gao
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6.  Case Report: A COVID-19 Patient Presenting with Mild Rhabdomyolysis.

Authors:  Betul Borku Uysal; Hande Ikitimur; Serap Yavuzer; Mehmet Sami Islamoglu; Mahir Cengiz
Journal:  Am J Trop Med Hyg       Date:  2020-06-19       Impact factor: 2.345

7.  Convalescent plasma transfusion for the treatment of COVID-19: Systematic review.

Authors:  Karthick Rajendran; Narayanasamy Krishnasamy; Jayanthi Rangarajan; Jeyalalitha Rathinam; Murugan Natarajan; Arunkumar Ramachandran
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8.  COVID-19-related myocarditis in a 21-year-old female patient.

Authors:  In-Cheol Kim; Jin Young Kim; Hyun Ah Kim; Seongwook Han
Journal:  Eur Heart J       Date:  2020-05-14       Impact factor: 29.983

9.  COVID-19-associated pancytopenia can be self-limiting and does not necessarily warrant bone marrow biopsy for the purposes of SARS-CoV-2 diagnostics.

Authors:  D S Hersby; T H Do; A O Gang; T H Nielsen
Journal:  Ann Oncol       Date:  2020-10-01       Impact factor: 32.976

10.  Coronavirus disease associated immune thrombocytopenia: Causation or correlation?

Authors:  Simona Pascolini; Alessandro Granito; Luigi Muratori; Marco Lenzi; Paolo Muratori
Journal:  J Microbiol Immunol Infect       Date:  2020-08-18       Impact factor: 4.399

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  1 in total

Review 1.  Concurrent myopathy and inflammatory cardiac disease in COVID-19 patients: a case series and literature review.

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Journal:  Rheumatol Int       Date:  2022-03-11       Impact factor: 3.580

  1 in total

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