| Literature DB >> 33551954 |
James E Galvin1, Paul Aisen2, Jessica B Langbaum3, Eric Rodriguez4, Marwan Sabbagh5, Richard Stefanacci6, Robert A Stern7, Elizabeth A Vassey7, Arno de Wilde8, Neva West9, Ivana Rubino9.
Abstract
Alzheimer's disease (AD) is a progressive, neurodegenerative disease that creates complex challenges and a significant burden for patients and caregivers. Although underlying pathological changes due to AD may be detected in research studies decades prior to symptom onset, many patients in the early stages of AD remain undiagnosed in clinical practice. Increasing evidence points to the importance of an early and accurate AD diagnosis to optimize outcomes for patients and their families, yet many barriers remain along the diagnostic journey. Through a series of international working group meetings, a diverse group of experts contributed their perspectives to create a blueprint for a patient-centered diagnostic journey for individuals in the early stages of AD and an evolving, transdisciplinary care team. Here, we discuss key learnings, implications, and recommendations.Entities:
Keywords: Alzheimer's disease; dementia; diagnosis; early detection; mild cognitive impairment
Year: 2021 PMID: 33551954 PMCID: PMC7863984 DOI: 10.3389/fneur.2020.592302
Source DB: PubMed Journal: Front Neurol ISSN: 1664-2295 Impact factor: 4.003