Eilon Shany1,2, Kyla Marks3,4, Aviva Levitas3,5, Agneta Golan3,4, Ramy Abramsky3,4, Benjamin H Taragin3,6, Ilan Shelef3,6. 1. Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva, Israel, eshany@bgu.ac.il. 2. Neonatal Department, Soroka Medical Center, Beer-Sheva, Israel, eshany@bgu.ac.il. 3. Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva, Israel. 4. Neonatal Department, Soroka Medical Center, Beer-Sheva, Israel. 5. Pediatric Cardiology Unit, Soroka Medical Center, Beer-Sheva, Israel. 6. Radiology Department, Soroka Medical Center, Beer-Sheva, Israel.
Abstract
BACKGROUND: Recent reports advocate the use of MRI either as a substitute for postmortem examinations or for a more targeted autopsy. METHODS: A full-body postmortem MRI (pMRI) of infants was performed as early as possible after death, and findings were compared to clinical premortem diagnoses. RESULTS: Thirty-one infants were scanned during the study period. Median gestation at birth was 34 weeks (ranges: 24-43). In 3 (10%) cases, no new findings were detected. In 2 (6%), new minor findings not related to the cause of death were detected, and in 17 (55%), new minor findings related to the cause of death were detected. New major findings related to the cause of death were detected in 4 (13%) cases, and new major findings not related to the cause of death were detected in 5 (16%) cases. In 3 (10%), findings thought to alter the perceived cause of death were detected. Overall, in 23 (74%) cases, pMRI findings reinforced the clinical premortem diagnoses. CONCLUSIONS: pMRI is a culturally accepted alternative when autopsy is not performed and can either reinforce, refute, or add to premortem clinical diagnoses.
BACKGROUND: Recent reports advocate the use of MRI either as a substitute for postmortem examinations or for a more targeted autopsy. METHODS: A full-body postmortem MRI (pMRI) of infants was performed as early as possible after death, and findings were compared to clinical premortem diagnoses. RESULTS: Thirty-one infants were scanned during the study period. Median gestation at birth was 34 weeks (ranges: 24-43). In 3 (10%) cases, no new findings were detected. In 2 (6%), new minor findings not related to the cause of death were detected, and in 17 (55%), new minor findings related to the cause of death were detected. New major findings related to the cause of death were detected in 4 (13%) cases, and new major findings not related to the cause of death were detected in 5 (16%) cases. In 3 (10%), findings thought to alter the perceived cause of death were detected. Overall, in 23 (74%) cases, pMRI findings reinforced the clinical premortem diagnoses. CONCLUSIONS: pMRI is a culturally accepted alternative when autopsy is not performed and can either reinforce, refute, or add to premortem clinical diagnoses.