| Literature DB >> 33549473 |
Kutluk H Oktay1, Loris Marin2, Boris Petrikovsky3, Michael Terrani4, Samir N Babayev5.
Abstract
Ovarian tissue cryopreservation and autotransplantation can restore ovarian endocrine function and fertility and recently were changed from experimental to fertility preservation procedures for medical indications by the American Society of Reproductive Medicine. Such advances have resulted in discussions around the utility of ovarian cryopreservation in healthy women to preserve fertility and delay menopause or as a hormone replacement approach. Such 'elective' use of ovarian tissue cryopreservation requires a risk-benefit assessment. Here, we review evidence for and against the utility of ovarian tissue harvesting in healthy women, scrutinize recent and needed advances to enhance the feasibility of such an approach, and provide practice and future research guidelines.Entities:
Keywords: elective fertility preservation; fertility preservation in healthy women; ovarian tissue cryopreservation and transplantation; reproductive aging; translational research
Mesh：
Year: 2021 PMID： 33549473 PMCID： PMC8427891 DOI： 10.1016/j.molmed.2021.01.005
Source DB: PubMed Journal: Trends Mol Med ISSN： 1471-4914 Impact factor: 15.272